Area of research
Virology · Immunology
Research interest
Research interests include HIV Research and Treatment, Immune Cell Function and Interaction, T-cell and B-cell Immunology, and COVID-19 Clinical Research Studies.
System vaccinology analysis of predictors and mechanisms of antibody response durability to multiple vaccines in humans
Diverse priming outcomes under conditions of very rare precursor B cells
A multiomics recovery factor predicts long COVID in the IMPACC study
Identifying correlates of viral rebound timing and viral control in SHIV-infected infant macaques after ART interruption
Type 2 immune responses are associated with less severe COVID-19 in a hospitalized cohort
MICBG406A polymorphism reduces risk of mechanical ventilation and death during viral acute lung injury
Identification of a multi-omics factor predictive of long COVID in the IMPACC study
Baseline predictors for 28-day COVID-19 severity and mortality among hospitalized patients: results from the IMPACC study
Minimalistic transcriptomic signatures permit accurate early prediction of COVID-19 mortality
Vaccine priming of rare HIV broadly neutralizing antibody precursors in nonhuman primates
Features of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study
The CARD8 inflammasome dictates HIV/SIV pathogenesis and disease progression
Integrated longitudinal multiomics study identifies immune programs associated with acute COVID-19 severity and mortality
Distinct SIV-specific CD8+ T cells in the lymph node exhibit simultaneous effector and stem-like profiles and are associated with limited SIV persistence
Unraveling SARS-CoV-2 Host-Response Heterogeneity through Longitudinal Molecular Subtyping
Multi-omics analysis of mucosal and systemic immunity to SARS-CoV-2 after birth
CD8+ T cells promote HIV latency by remodeling CD4+ T cell metabolism to enhance their survival, quiescence, and stemness
TREM2+ and interstitial-like macrophages orchestrate airway inflammation in SARS-CoV-2 infection in rhesus macaques
Modulation of type I interferon responses potently inhibits SARS-CoV-2 replication and inflammation in rhesus macaques
Copper intrauterine device increases vaginal concentrations of inflammatory anaerobes and depletes lactobacilli compared to hormonal options in a randomized trial
Intradermal but not intramuscular modified vaccinia Ankara immunizations protect against intravaginal tier2 simian-human immunodeficiency virus challenges in female macaques
Integrated longitudinal multi-omics study identifies immune programs associated with COVID-19 severity and mortality in 1152 hospitalized participants
Systems biological assessment of the temporal dynamics of immunity to a viral infection in the first weeks and months of life
Infiltration of inflammatory macrophages and neutrophils and widespread pyroptosis in lung drive influenza lethality in nonhuman primates
From structure to sequence: Antibody discovery using cryoEM
Interleukin-10 contributes to reservoir establishment and persistence in SIV-infected macaques treated with antiretroviral therapy
DOAJ (DOAJ: Directory of Open Access Journals) 2022cited by 41position: middle
Systems vaccinology of the BNT162b2 mRNA vaccine in humans
The single-cell epigenomic and transcriptional landscape of immunity to influenza vaccination
Phase II Trial of Costimulation Blockade With Abatacept for Prevention of Acute GVHD
A modified vaccinia Ankara vector-based vaccine protects macaques from SARS-CoV-2 infection, immune pathology, and dysfunction in the lungs
Functional Omics Core Laboratory
Illumina NovaSeq X Plus High Throughput DNA Sequencer for Emory University
Population genotyping of the germline immunoglobulin repertoire in AIDS-designated rhesus macaque breeding colonies
Population genotyping of the germline immunoglobulin repertoire in AIDS-designated rhesus macaque breeding colonies
Population genotyping of the germline immunoglobulin repertoire in AIDS-designated rhesus macaque breeding colonies
Population genotyping of the germline immunoglobulin repertoire in AIDS-designated rhesus macaque breeding colonies
Population genotyping of the germline immunoglobulin repertoire in AIDS-designated rhesus macaque breeding colonies
Population genotyping of the germline immunoglobulin repertoire in AIDS-designated rhesus macaque breeding colonies
Maintenance of the SPF Breeding Colonies at Yerkes National Primate Research Center: Husbandry and Management Core
Project 2: Innate Immunity
Illumina NovaSeq 6000 High Throughput DNA Sequencer for Emory University
Maintenance of the SPF Breeding Colonies at Yerkes National Primate Research Center: Husbandry and Management Core
Project 2: Innate Immunity
Blocking type I interferon signaling to reverse T cell exhaustion and control HIV-1 reservoirs
Blocking type I interferon signaling to reverse T cell exhaustion and control HIV-1 reservoirs
Blocking type I interferon signaling to reverse T cell exhaustion and control HIV-1 reservoirs
Blocking type I interferon signaling to reverse T cell exhaustion and control HIV-1 reservoirs
Maintenance of the SPF Breeding Colonies at Yerkes National Primate Research Center: Husbandry and Management Core
Blocking type I interferon signaling to reverse T cell exhaustion and control HIV-1 reservoirs
Blocking type I interferon signaling to reverse T cell exhaustion and control HIV-1 reservoirs
Using DNA/MVA/protein immunization of rhesus macaques to investigate how the background of the HIV-1 envelope and nature of the protein boost shape the genetic and functional antibody landscape.
Development of multi-modal single-cell technology to dissect epitope specificity to HIV
Development of multi-modal single-cell technology to dissect epitope specificity to HIV
Development of multi-modal single-cell technology to dissect epitope specificity to HIV
Development of multi-modal single-cell technology to dissect epitope specificity to HIV