Area of research
Hematology · Molecular Biology
Research interest
Research interests include Acute Myeloid Leukemia Research, Retinoids in leukemia and cellular processes, Acute Lymphoblastic Leukemia research, and Chronic Myeloid Leukemia Treatments.
Effective Treatment of Disseminated Prostate Cancer Using CD46-Targeted 225Ac Therapy
The SWI/SNF chromatin-remodeling subunit DPF2 facilitates NRF2-dependent antiinflammatory and antioxidant gene expression
LNK/<i>SH2B3</i> as a novel driver in juvenile myelomonocytic leukemia
RASA2 ablation in T cells boosts antigen sensitivity and long-term function
Genetic disruption of N-RasG12D palmitoylation perturbs hematopoiesis and prevents myeloid transformation in mice
KrasP34R and KrasT58I mutations induce distinct RASopathy phenotypes in mice
Pml nuclear body disruption cooperates in APL pathogenesis and impairs DNA damage repair pathways in mice
DNMT3A Haploinsufficiency Transforms <i>FLT3</i> ITD Myeloproliferative Disease into a Rapid, Spontaneous, and Fully Penetrant Acute Myeloid Leukemia
In utero cytomegalovirus infection and development of childhood acute lymphoblastic leukemia
Mechanisms of clonal evolution in childhood acute lymphoblastic leukemia
Cooperative loss of RAS feedback regulation drives myeloid leukemogenesis
Direct and indirect targeting of MYC to treat acute myeloid leukemia
MLL3 Is a Haploinsufficient 7q Tumor Suppressor in Acute Myeloid Leukemia
Crenolanib is a selective type I pan-FLT3 inhibitor
Preclinical efficacy of MEK inhibition in Nras-mutant AML
CUL4A Induces Epithelial–Mesenchymal Transition and Promotes Cancer Metastasis by Regulating ZEB1 Expression
The Histone Demethylase PHF8 Governs Retinoic Acid Response in Acute Promyelocytic Leukemia
Pten loss in the bone marrow leads to G-CSF–mediated HSC mobilization
Sustained MEK inhibition abrogates myeloproliferative disease in Nf1 mutant mice
An insertional mutagenesis screen identifies genes that cooperate with Mll-AF9 in a murine leukemogenesis model