Area of research
Genetics · Organic Chemistry
Research interest
Research interests include Biology, Glucocorticoid receptor, Transcription factor, Cancer research, Computational biology, and Ligand (biochemistry).
Hydroxychloroquine blocks SARS-CoV-2 entry into the endocytic pathway in mammalian cell culture
The SARS-CoV-2 spike protein binds and modulates estrogen receptors
Chemical systems biology reveals mechanisms of glucocorticoid receptor signaling
Cryptic glucocorticoid receptor-binding sites pervade genomic NF-κB response elements
The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells
Structural and Molecular Mechanisms of Cytokine-Mediated Endocrine Resistance in Human Breast Cancer Cells
Tethering not required: the glucocorticoid receptor binds directly to activator protein-1 recognition motifs to repress inflammatory genes
Full antagonism of the estrogen receptor without a prototypical ligand side chain
Systems Structural Biology Analysis of Ligand Effects on ERα Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies