Area of research
Cardiology and Cardiovascular Medicine · Molecular Biology
Research interest
Research interests include Titin, Protein filament, Cardiology, Sarcomere, Immunoglobulin domain, and Biophysics.
Alternative Splicing of Titin Restores Diastolic Function in an HFpEF-Like Genetic Murine Model ( <i>Ttn</i> <sup>ΔIAjxn</sup> )
Knockout of Lmod2 results in shorter thin filaments followed by dilated cardiomyopathy and juvenile lethality
Deleting titin’s I-band/A-band junction reveals critical roles for titin in biomechanical sensing and cardiac function
Increased myocardial stiffness due to cardiac titin isoform switching in a mouse model of volume overload limits eccentric remodeling
Endurance Exercise Accelerates Myocardial Tissue Oxygenation Recovery and Reduces Ischemia Reperfusion Injury in Mice
Cardiac Fibroblast-Dependent Extracellular Matrix Accumulation Is Associated with Diastolic Stiffness in Type 2 Diabetes
The multifunctional Ca2+/calmodulin-dependent protein kinase II delta (CaMKIIδ) phosphorylates cardiac titin's spring elements