Area of research
Cardiology and Cardiovascular Medicine · Molecular Biology
Research interest
Research interests include Titin, Sarcomere, Obscurin, Skeletal muscle, Medicine, and Protein filament.
Phosphodiesterase 9a Inhibition in Mouse Models of Diastolic Dysfunction
Nebulin and Lmod2 are critical for specifying thin-filament length in skeletal muscle
Single-Molecule Force Spectroscopy on the N2A Element of Titin: Effects of Phosphorylation and CARP
Titin mutations and muscle disease
Fine mapping titin's C-zone: Matching cardiac myosin-binding protein C stripes with titin's super-repeats
Titin splicing regulates cardiotoxicity associated with calpain 3 gene therapy for limb-girdle muscular dystrophy type 2A
Congenital Titinopathy: Comprehensive characterization and pathogenic insights
Downsizing the molecular spring of the giant protein titin reveals that skeletal muscle titin determines passive stiffness and drives longitudinal hypertrophy
The giant protein titin regulates the length of the striated muscle thick filament
Novex-3, the tiny titin of muscle
Nebulin deficiency in adult muscle causes sarcomere defects and muscle-type-dependent changes in trophicity: novel insights in nemaline myopathy
Phosphorylating Titin’s Cardiac N2B Element by ERK2 or CaMKIIδ Lowers the Single Molecule and Cardiac Muscle Force
Deleting titin’s I-band/A-band junction reveals critical roles for titin in biomechanical sensing and cardiac function
Removal of immunoglobulin-like domains from titin’s spring segment alters titin splicing in mouse skeletal muscle and causes myopathy