Area of research
Molecular Biology · Public Health, Environmental and Occupational Health
Research interest
Research interests include DNA Repair Mechanisms, Biochemical and Molecular Research, Acute Lymphoblastic Leukemia research, and HIV/AIDS drug development and treatment.
Understanding the interplay between dNTP metabolism and genome stability in cancer
Targeting pan-essential pathways in cancer with cytotoxic chemotherapy: challenges and opportunities
Targeting the DNA damage response and repair in cancer through nucleotide metabolism
NUDT15-mediated hydrolysis limits the efficacy of anti-HCMV drug ganciclovir
Ribonucleotide reductase inhibitors suppress SAMHD1 ara‐CTPase activity enhancing cytarabine efficacy
Nucleobase and Nucleoside Analogues: Resistance and Re-Sensitisation at the Level of Pharmacokinetics, Pharmacodynamics and Metabolism
Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells
Targeting SAMHD1 with the Vpx protein to improve cytarabine therapy for hematological malignancies
SAMHD1 protects cancer cells from various nucleoside-based antimetabolites
Validation and development of MTH1 inhibitors for treatment of cancer
Pathways controlling dNTP pools to maintain genome stability
PrimPol—A new polymerase on the block
PPL2 Translesion Polymerase Is Essential for the Completion of Chromosomal DNA Replication in the African Trypanosome