Area of research
Molecular Biology · Cell Biology
Research interest
Research interests include Ubiquitin and proteasome pathways, Endoplasmic Reticulum Stress and Disease, Protein Degradation and Inhibitors, and Signaling Pathways in Disease.
Structural basis for the midnolin-proteasome pathway and its role in suppressing myeloma
A heterotrimeric protein complex assembles the metazoan V-ATPase upon dissipation of proton gradients
An RNA splicing system that excises DNA transposons from animal mRNAs
Structure of the TXNL1-bound proteasome
The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation
A central role for regulated protein stability in the control of TFE3 and MITF by nutrients
Elucidation of E3 ubiquitin ligase specificity through proteome-wide internal degron mapping