Area of research
Virology · Radiology, Nuclear Medicine and Imaging
Research interest
Research interests include HIV Research and Treatment, Monoclonal and Polyclonal Antibodies Research, Glycosylation and Glycoproteins Research, and HIV/AIDS drug development and treatment.
Precise targeting of HIV broadly neutralizing antibody precursors in humans
Germline-targeting HIV vaccination induces neutralizing antibodies to the CD4 binding site
Immunization with germ line–targeting SOSIP trimers elicits broadly neutralizing antibody precursors in infant macaques
Exposure of progressive immune dysfunction by SARS-CoV-2 mRNA vaccination in patients with chronic lymphocytic leukemia: A prospective cohort study
Antibody Responses to SARS-CoV-2 mRNA Vaccines Are Detectable in Saliva
Enhancing glycan occupancy of soluble HIV-1 envelope trimers to mimic the native viral spike
Predictors of Nonseroconversion after SARS-CoV-2 Infection
Neutralizing Antibody Induction by HIV-1 Envelope Glycoprotein SOSIP Trimers on Iron Oxide Nanoparticles May Be Impaired by Mannose Binding Lectin
Open and closed structures reveal allostery and pliability in the HIV-1 envelope spike
Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo
Glycosylation Benchmark Profile for HIV-1 Envelope Glycoprotein Production Based on Eleven Env Trimers
cGMP production and analysis of BG505 SOSIP.664, an extensively glycosylated, trimeric HIV‐1 envelope glycoprotein vaccine candidate
Reducing V3 Antigenicity and Immunogenicity on Soluble, Native-Like HIV-1 Env SOSIP Trimers
Composition and Antigenic Effects of Individual Glycan Sites of a Trimeric HIV-1 Envelope Glycoprotein
Sequential and Simultaneous Immunization of Rabbits with HIV-1 Envelope Glycoprotein SOSIP.664 Trimers from Clades A, B and C
Molecular Architecture of the Cleavage-Dependent Mannose Patch on a Soluble HIV-1 Envelope Glycoprotein Trimer
HIV-1 neutralizing antibodies induced by native-like envelope trimers
Immunization for HIV-1 Broadly Neutralizing Antibodies in Human Ig Knockin Mice
A Native-Like SOSIP.664 Trimer Based on an HIV-1 Subtype B <i>env</i> Gene
Murine Antibody Responses to Cleaved Soluble HIV-1 Envelope Trimers Are Highly Restricted in Specificity
Antibody potency relates to the ability to recognize the closed, pre-fusion form of HIV Env
Structural Constraints Determine the Glycosylation of HIV-1 Envelope Trimers
Design and structure of two HIV-1 clade C SOSIP.664 trimers that increase the arsenal of native-like Env immunogens
Comprehensive Antigenic Map of a Cleaved Soluble HIV-1 Envelope Trimer
Influences on the Design and Purification of Soluble, Recombinant Native-Like HIV-1 Envelope Glycoprotein Trimers
Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies
Structural Delineation of a Quaternary, Cleavage-Dependent Epitope at the gp41-gp120 Interface on Intact HIV-1 Env Trimers
Structural Evolution of Glycan Recognition by a Family of Potent HIV Antibodies
Differential binding of neutralizing and non-neutralizing antibodies to native-like soluble HIV-1 Env trimers, uncleaved Env proteins, and monomeric subunits
CD4-Induced Activation in a Soluble HIV-1 Env Trimer