Area of research
Virology · Radiology, Nuclear Medicine and Imaging
Research interest
Research interests include Antibody, Virology, Epitope, Biology, Trimer, and Neutralizing antibody.
Vaccination with mRNA-encoded nanoparticles drives early maturation of HIV bnAb precursors in humans
Precise targeting of HIV broadly neutralizing antibody precursors in humans
Vaccination with mRNA-encoded membrane-anchored HIV envelope trimers elicited tier 2 neutralizing antibodies in a phase 1 clinical trial
Vaccines combining slow release and follicle targeting of antigens increase germinal center B cell diversity and clonal expansion
Vaccination with an mRNA-encoded membrane-bound HIV envelope trimer induces neutralizing antibodies in animal models
HIV broadly neutralizing antibody precursors to the Apex epitope induced in nonhuman primates
Microfluidics combined with electron microscopy for rapid and high-throughput mapping of antibody–viral glycoprotein complexes
Vaccination of nonhuman primates elicits a broadly neutralizing antibody lineage targeting a quaternary epitope on the HIV-1 Env trimer
Germline-targeting HIV immunogen induces cross-neutralizing antibodies in outbred macaques
Accelerated cGMP production of near-native HIV-1 Env trimers following electroporation transfection and immunogenicity analysis
mRNA-LNP HIV-1 trimer boosters elicit precursors to broad neutralizing antibodies
Vaccine priming of rare HIV broadly neutralizing antibody precursors in nonhuman primates
Vaccination induces broadly neutralizing antibody precursors to HIV gp41
Germline-targeting HIV vaccination induces neutralizing antibodies to the CD4 binding site
Use of 3M-052-AF with Alum adjuvant in HIV trimer vaccine induces human autologous neutralizing antibodies
Immunization with germ line–targeting SOSIP trimers elicits broadly neutralizing antibody precursors in infant macaques
Germline-targeting HIV-1 Env vaccination induces VRC01-class antibodies with rare insertions
A combined adjuvant approach primes robust germinal center responses and humoral immunity in non-human primates
Author Correction: Long-primed germinal centres with enduring affinity maturation and clonal migration
Site of vulnerability on SARS-CoV-2 spike induces broadly protective antibody against antigenically distinct Omicron subvariants
Long-primed germinal centres with enduring affinity maturation and clonal migration
From structure to sequence: Antibody discovery using cryoEM
Induction of cross-neutralizing antibodies by a permuted hepatitis C virus glycoprotein nanoparticle vaccine candidate
Molecular insights into antibody-mediated protection against the prototypic simian immunodeficiency virus
Isolation and characterization of cross-neutralizing coronavirus antibodies from COVID-19+ subjects
Enhancing glycan occupancy of soluble HIV-1 envelope trimers to mimic the native viral spike
Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates
Autologous Antibody Responses to an HIV Envelope Glycan Hole Are Not Easily Broadened in Rabbits
A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses
Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence