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François Ghiringhelli

Peuplements végétaux et bioagresseurs en milieu tropical · FR
Area of research
Oncology · Immunology
Research interest
Research interests include Cancer Immunotherapy and Biomarkers, Immunotherapy and Immune Responses, Colorectal Cancer Treatments and Studies, and Immune Cell Function and Interaction.
h-index
107
citations
58,915
works
956
NIH funding
primary concept
Medicine
email

Recent publications

Lenvatinib Plus Pembrolizumab and Chemotherapy Versus Chemotherapy in Advanced Metastatic Gastroesophageal Adenocarcinoma: The Phase III, Randomized LEAP-015 Study
Journal of Clinical Oncology 2025cited by 14position: middledoi
Phase II Dose-Randomized Study of Sunvozertinib in Platinum-Pretreated Non–Small Cell Lung Cancer With Epidermal Growth Factor Receptor Exon 20 Insertion Mutations (WU-KONG1B)
Journal of Clinical Oncology 2025cited by 10position: middledoi
Efficacy of pembrolizumab and vorinostat combination in patients with recurrent and/or metastatic squamous cell carcinomas: a phase 2 basket trial
Nature Cancer 2025cited by 9position: middledoi
Genetic biomarker study of sunvozertinib for clinical prognosis and prediction in NSCLC with EGFR exon 20 insertion mutation
Cell Reports Medicine 2025cited by 4position: middledoi
Mimicry-based strategy between human and commensal antigens for the development of a new family of immune therapies for cancer
Journal for ImmunoTherapy of Cancer 2025cited by 3position: middledoi
Fruquintinib in less pretreated patients: Multivariate profile-matching analysis of FRESCO-2 to FRESCO
European Journal of Cancer 2025cited by 2position: middledoi
P12.59.B CONDITIONAL SURVIVAL ANALYSIS IN IDH-MUTANT HIGH-GRADE GLIOMAS: AN USEFUL TOOL IN CLINICAL PRACTICE
Neuro-Oncology 2025cited by 0position: middledoi
BIOS-01. CONDITIONAL SURVIVAL ANALYSIS IN IDH-MUTANT HIGH-GRADE GLIOMAS: AN USEFUL TOOL IN CLINICAL PRACTICE
Neuro-Oncology 2025cited by 0position: middledoi
Custom scoring based on ecological topology of gut microbiota associated with cancer immunotherapy outcome
Cell 2024cited by 154position: middledoi
Gemcitabine and Paclitaxel Versus Gemcitabine Alone After 5-Fluorouracil, Oxaliplatin, and Irinotecan in Metastatic Pancreatic Adenocarcinoma: A Randomized Phase III PRODIGE 65-UCGI 36-GEMPAX UNICANCER Study
Journal of Clinical Oncology 2024cited by 33position: lastdoi
Survival Outcomes Associated With First-Line Procarbazine, CCNU, and Vincristine or Temozolomide in Combination With Radiotherapy in IDH-Mutant 1p/19q-Codeleted Grade 3 Oligodendroglioma
Journal of Clinical Oncology 2024cited by 27position: middledoi
First-in-human study of ABBV-400, a novel c-Met–targeting antibody-drug conjugate, in advanced solid tumors: Results in colorectal cancer.
Journal of Clinical Oncology 2024cited by 13position: middledoi
Fruquintinib versus placebo in patients with refractory metastatic colorectal cancer (FRESCO-2): an international, multicentre, randomised, double-blind, phase 3 study
The Lancet 2023cited by 311position: middledoi
Tucatinib plus trastuzumab for chemotherapy-refractory, HER2-positive, RAS wild-type unresectable or metastatic colorectal cancer (MOUNTAINEER): a multicentre, open-label, phase 2 study
The Lancet Oncology 2023cited by 238position: middledoi
A microbiota-modulated checkpoint directs immunosuppressive intestinal T cells into cancers
Science 2023cited by 210position: middledoi
Developing a definition of immune exclusion in cancer: results of a modified Delphi workshop
Journal for ImmunoTherapy of Cancer 2023cited by 39position: middledoi
Paclitaxel plus carboplatin and durvalumab with or without oleclumab for women with previously untreated locally advanced or metastatic triple-negative breast cancer: the randomized SYNERGY phase I/II trial
Nature Communications 2023cited by 26position: middledoi
First-line lenvatinib plus pembrolizumab plus chemotherapy versus chemotherapy in advanced/metastatic gastroesophageal adenocarcinoma (LEAP-015): Safety run-in results.
Journal of Clinical Oncology 2023cited by 15position: middledoi
EO2401 (E) peptide immunotherapy + nivolumab (N) +/- bevacizumab (B) in recurrent glioblastoma (GB): EOGBM1-18/ROSALIE.
Journal of Clinical Oncology 2023cited by 1position: middledoi
Intestinal Akkermansia muciniphila predicts clinical response to PD-1 blockade in patients with advanced non-small-cell lung cancer
Nature Medicine 2022cited by 624position: middledoi
Immunologically active phenotype by gene expression profiling is associated with clinical benefit from PD-1/PD-L1 inhibitors in real-world head and neck and lung cancer patients
European Journal of Cancer 2022cited by 66position: middledoi
Datasets for gene expression profiles of head and neck squamous cell carcinoma and lung cancer treated or not by PD1/PD-L1 inhibitors
Data in Brief 2022cited by 19position: middledoi
Atezolizumab plus modified DCF (docetaxel, cisplatin, and 5-fluorouracil) as first-line treatment for metastatic or locally advanced squamous cell anal carcinoma: A SCARCE-PRODIGE 60 randomized phase II study.
Journal of Clinical Oncology 2022cited by 17position: middledoi
Incidence and characteristics of pseudoprogression in IDH-mutant high-grade gliomas: A POLA network study
Neuro-Oncology 2022cited by 16position: middledoi
EO2401, a novel microbiome-derived therapeutic vaccine for patients with recurrent glioblastoma: ROSALIE study.
Journal of Clinical Oncology 2022cited by 8position: middledoi
1223P First-line lenvatinib (Len) + pembrolizumab (Pembro) + chemotherapy (Chemo) vs chemo in advanced/metastatic gastroesophageal adenocarcinoma: LEAP-015 safety run-in
Annals of Oncology 2022cited by 5position: middledoi
642 EO2401 microbiome derived therapeutic vaccine + nivolumab, with/without standard continuous, or low-dose symptom directed, bevacizumab, in recurrent glioblastoma: phase 1–2 EOGBM1–18/ROSALIE study
Regular and Young Investigator Award Abstracts 2022cited by 4position: middledoi
CTIM-17. EO2401 THERAPEUTIC VACCINE FOR PATIENTS WITH RECURRENT GLIOBLASTOMA: PHASE 1/2 ROSALIE STUDY (NCT04116658)
Neuro-Oncology 2022cited by 3position: middledoi
Intestinal microbiota influences clinical outcome and side effects of early breast cancer treatment
Cell Death and Differentiation 2021cited by 163position: middledoi
Cross-reactivity between tumor MHC class I–restricted antigens and an enterococcal bacteriophage
Science 2020cited by 377position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

David A. Reardon · Massachusetts Institute of Technology4 papers (2022–2023)Agostina Stradella · Ajuntament de L’Hospitalet4 papers (2022–2023)Mehdi Touat · Université Paris 1 Panthéon-Sorbonne4 papers (2022–2023)Wolfgang Wick · Heidelberger Institut für Radioonkologie4 papers (2022–2023)Lionel Apétoh · University of Lausanne4 papers (2012–2017)Ghazaleh Tabatabai · Goethe University Frankfurt4 papers (2022–2023)Ahmed Idbaïh · Institut de Myologie4 papers (2022–2023)Ana Maia · The Netherlands Cancer Institute4 papers (2022–2023)Mirjam Renovanz · University Children's Hospital Tübingen4 papers (2022–2023)María Vieito · Instituto de Investigación Sanitaria de Santiago4 papers (2022–2023)Iris Mildenberger · German Cancer Research Center4 papers (2022–2023)Patrick Y. Wen · Harvard University4 papers (2022–2023)Antje Wick · Heidelberg University4 papers (2022–2023)Sylvain Ladoire · Université de franche-comté3 papers (2012–2017)Ulrich Herrlinger · Brain (Germany)3 papers (2022–2023) · 3 papers (2022–2023)Christophe Bonny · University of Lausanne3 papers (2022–2023)Cécile Gouttefangeas · German Cancer Research Center3 papers (2022–2022)Michael C. Burger · Goethe University Frankfurt3 papers (2022–2023) · 3 papers (2022–2023)