Stefan Christen

Trigonelline is an NAD+ precursor that improves muscle function during ageing and is reduced in human sarcopenia

mTORC1 regulates cell survival under glucose starvation through 4EBP1/2-mediated translational reprogramming of fatty acid metabolism

PFKFB4 interacts with FBXO28 to promote HIF-1α signaling in glioblastoma

4EBP1/2 support tumorigenicity and cell survival during energetic stress by translationally regulating fatty acid synthesis

SUCLA2 mutations cause global protein succinylation contributing to the pathomechanism of a hereditary mitochondrial disease

Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity

AMPK promotes survival of c‐Myc‐positive melanoma cells by suppressing oxidative stress

α-ketoglutarate orchestrates macrophage activation through metabolic and epigenetic reprogramming

Proline metabolism supports metastasis formation and could be inhibited to selectively target metastasizing cancer cells

Identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancers

Breast Cancer-Derived Lung Metastases Show Increased Pyruvate Carboxylase-Dependent Anaplerosis

Dual loss of succinate dehydrogenase (SDH) and complex I activity is necessary to recapitulate the metabolic phenotype of SDH mutant tumors

Fatty acid carbon is essential for dNTP synthesis in endothelial cells

Organ-Specific Cancer Metabolism and Its Potential for Therapy

Metabolic control of signalling pathways and metabolic auto‐regulation

Inferring causal metabolic signals that regulate the dynamic TORC1‐dependent transcriptome

Pyruvate Kinase Isoform Expression Alters Nucleotide Synthesis to Impact Cell Proliferation

Aneuploid yeast strains exhibit defects in cell growth and passage through START