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Ignacio Vázquez-Garćıa

Broad Institute ·
🔎 Find collaborators in Cancer Research · Molecular Biology →
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Area of research
Cancer Research · Molecular Biology
Research interest
Research interests include Cancer Genomics and Diagnostics, Single-cell and spatial transcriptomics, Evolution and Genetic Dynamics, and Genetic factors in colorectal cancer.
h-index
45
citations
22,159
works
107
NIH funding
primary concept
Biology
email

Recent publications

Ongoing genome doubling shapes evolvability and immunity in ovarian cancer
Nature 2025cited by 31position: middledoi
CINner: Modeling and simulation of chromosomal instability in cancer at single-cell resolution
PLoS Computational Biology 2025cited by 8position: middledoi
Cancer Research in the Age of Spatial Omics: Lessons from IMAXT
Cancer Discovery 2025cited by 4position: middledoi
Single-cell mtDNA dynamics in tumors is driven by coregulation of nuclear and mitochondrial genomes
Nature Genetics 2024cited by 24position: middledoi
Crowd-sourced benchmarking of single-sample tumor subclonal reconstruction
Nature Biotechnology 2024cited by 9position: middledoi
CINner: modeling and simulation of chromosomal instability in cancer at single-cell resolution
bioRxiv (Cold Spring Harbor Laboratory) 2024cited by 6position: middledoi
Author Correction: The repertoire of mutational signatures in human cancer
Nature 2023cited by 9position: middledoi
Imaging and Molecular Annotation of Xenographs and Tumours (IMAXT): High throughput data and analysis infrastructure
Biological Imaging 2023cited by 5position: middledoi
Multimodal data integration using machine learning improves risk stratification of high-grade serous ovarian cancer
Nature Cancer 2022cited by 333position: middledoi
Ovarian cancer mutational processes drive site-specific immune evasion
Nature 2022cited by 292position: firstdoi
Single-cell genomic variation induced by mutational processes in cancer
Nature 2022cited by 151position: middledoi
Fundamental immune–oncogenicity trade-offs define driver mutation fitness
Nature 2022cited by 79position: middledoi
Author Correction: Inferring structural variant cancer cell fraction
Nature Communications 2022cited by 0position: middledoi
Author Correction: Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig
Nature Communications 2022cited by 0position: middledoi
Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes
Cell 2021cited by 550position: middledoi
Three-dimensional imaging mass cytometry for highly multiplexed molecular and cellular mapping of tissues and the tumor microenvironment
Nature Cancer 2021cited by 213position: middledoi
Clonal fitness inferred from time-series modelling of single-cell cancer genomes
Nature 2021cited by 169position: middledoi
Landscapes of cellular phenotypic diversity in breast cancer xenografts and their impact on drug response
Nature Communications 2021cited by 58position: middledoi
The repertoire of mutational signatures in human cancer
Nature 2020cited by 3,686position: middledoi
The evolutionary history of 2,658 cancers
Nature 2020cited by 1,117position: middledoi
Imaging mass cytometry and multiplatform genomics define the phenogenomic landscape of breast cancer
Nature Cancer 2020cited by 330position: middledoi
Inferring structural variant cancer cell fraction
Nature Communications 2020cited by 56position: middledoi
Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig
Nature Communications 2020cited by 50position: middledoi
Characterizing Genetic Intra-Tumor Heterogeneity Across 2,658 Human Cancer Genomes
SSRN Electronic Journal 2020cited by 10position: middledoi
Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes
bioRxiv (Cold Spring Harbor Laboratory) 2018cited by 108position: middledoi
Portraits of genetic intra-tumour heterogeneity and subclonal selection across cancer types
2018cited by 44position: middle
The evolutionary history of 2,658 cancers
bioRxiv (Cold Spring Harbor Laboratory) 2017cited by 58position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Andrew McPherson · Provincial Health Services Authority3 papers (2024–2025)Adam C. Weiner · Gladstone Institutes3 papers (2024–2025)Khanh N. Dinh · Columbia University2 papers (2024–2025)Simon Tavaré · Ludwig Cancer Research2 papers (2024–2025)R. Malhotra · Palo Alto University2 papers (2024–2025) · 1 papers (2024–2024)Sonia Boscenco · Memorial Sloan Kettering Cancer Center1 papers (2024–2024) · 1 papers (2024–2024)Samuel Aparício · BC Cancer Agency1 papers (2024–2024)Ed Reznik · Motlow State Community College1 papers (2024–2024)Tyler Funnell · United States Geological Survey1 papers (2024–2024) · 1 papers (2024–2024)Marc Williams · Memorial Sloan Kettering Cancer Center1 papers (2024–2024)Payam A. Gammage · University of Glasgow1 papers (2024–2024)Hui Jiang · BGI Genomics1 papers (2024–2024)Minsoo Kim · Memorial Sloan Kettering Cancer Center1 papers (2024–2024)Cerise Tang · Memorial Sloan Kettering Cancer Center1 papers (2024–2024) · 1 papers (2024–2024) · 1 papers (2024–2024)Diljot Grewal · University of Tübingen1 papers (2024–2024)
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