← back to search

Andrew McPherson

Provincial Health Services Authority · US
Area of research
Cancer Research · Molecular Biology
Research interest
Research interests include Cancer Genomics and Diagnostics, Single-cell and spatial transcriptomics, Genomics and Phylogenetic Studies, and Genomic variations and chromosomal abnormalities.
h-index
40
citations
16,208
works
165
NIH funding
primary concept
Biology
email

Recent publications

Ongoing genome doubling shapes evolvability and immunity in ovarian cancer
Nature 2025cited by 31position: firstdoi
CINner: Modeling and simulation of chromosomal instability in cancer at single-cell resolution
PLoS Computational Biology 2025cited by 8position: middledoi
Genomics Define Malignant Transformation in Myeloma Precursor Conditions
Journal of Clinical Oncology 2025cited by 6position: middledoi
Cancer Research in the Age of Spatial Omics: Lessons from IMAXT
Cancer Discovery 2025cited by 4position: middledoi
Single-cell chromatin accessibility reveals malignant regulatory programs in primary human cancers
Science 2024cited by 41position: middledoi
Single-cell mtDNA dynamics in tumors is driven by coregulation of nuclear and mitochondrial genomes
Nature Genetics 2024cited by 24position: middledoi
CINner: modeling and simulation of chromosomal instability in cancer at single-cell resolution
bioRxiv (Cold Spring Harbor Laboratory) 2024cited by 6position: middledoi
Epigenetic dysregulation from chromosomal transit in micronuclei
Nature 2023cited by 114position: middledoi
Tracking the Evolution of Therapy-Related Myeloid Neoplasms Using Chemotherapy Signatures
Blood 2023cited by 37position: middledoi
Multimodal data integration using machine learning improves risk stratification of high-grade serous ovarian cancer
Nature Cancer 2022cited by 333position: middledoi
Ovarian cancer mutational processes drive site-specific immune evasion
Nature 2022cited by 292position: middledoi
Single-cell genomic variation induced by mutational processes in cancer
Nature 2022cited by 151position: middledoi
Clonal somatic copy number altered driver events inform drug sensitivity in high-grade serous ovarian cancer
Nature Communications 2022cited by 41position: middledoi
Expansion sequencing: Spatially precise in situ transcriptomics in intact biological systems
Science 2021cited by 410position: middledoi
Three-dimensional imaging mass cytometry for highly multiplexed molecular and cellular mapping of tissues and the tumor microenvironment
Nature Cancer 2021cited by 213position: middledoi
Tim-4+ cavity-resident macrophages impair anti-tumor CD8+ T cell immunity
Cancer Cell 2021cited by 170position: middledoi
Landscapes of cellular phenotypic diversity in breast cancer xenografts and their impact on drug response
Nature Communications 2021cited by 58position: middledoi
Imaging mass cytometry and multiplatform genomics define the phenogenomic landscape of breast cancer
Nature Cancer 2020cited by 330position: middledoi
Probabilistic cell-type assignment of single-cell RNA-seq for tumor microenvironment profiling
Nature Methods 2019cited by 422position: middledoi
Interfaces of Malignant and Immunologic Clonal Dynamics in Ovarian Cancer
Cell 2018cited by 383position: middledoi
A survey of best practices for RNA-seq data analysis
Genome biology 2016cited by 2,858position: middledoi
Divergent modes of clonal spread and intraperitoneal mixing in high-grade serous ovarian cancer
Nature Genetics 2016cited by 367position: firstdoi
Histological Transformation and Progression in Follicular Lymphoma: A Clonal Evolution Study
PLoS Medicine 2016cited by 241position: middledoi
Erratum to: A survey of best practices for RNA-seq data analysis
Genome biology 2016cited by 169position: middledoi
Spatial genomic heterogeneity within localized, multifocal prostate cancer
Nature Genetics 2015cited by 486position: middledoi
Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution
Nature 2014cited by 634position: middledoi
The clonal and mutational evolution spectrum of primary triple-negative breast cancers
Nature 2012cited by 2,019position: middledoi
14-3-3 fusion oncogenes in high-grade endometrial stromal sarcoma
Proceedings of the National Academy of Sciences 2012cited by 256position: middledoi
From sequence to molecular pathology, and a mechanism driving the neuroendocrine phenotype in prostate cancer
The Journal of Pathology 2012cited by 195position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Adam C. Weiner · Gladstone Institutes3 papers (2024–2025)Sohrab P. Shah · Columbia University Irving Medical Center3 papers (2012–2024)Ignacio Vázquez-Garćıa · Broad Institute3 papers (2024–2025)Khanh N. Dinh · Columbia University2 papers (2024–2025)Simon Tavaré · Ludwig Cancer Research2 papers (2024–2025)Laura L. Elo · Tulane University2 papers (2016–2016)Jessica N. McAlpine · BC Cancer Agency2 papers (2012–2019)Samuel Aparício · BC Cancer Agency2 papers (2019–2024)A Mortazavi · California Institute of Technology2 papers (2016–2016)David Gómez-Cabrero · King's College London2 papers (2016–2016) · 2 papers (2016–2016)Xuegong Zhang · Ministry of Education of the People's Republic of China2 papers (2016–2016)R. Malhotra · Palo Alto University2 papers (2024–2025)Ana Conesa · University of Florida2 papers (2016–2016)Daniel J. Gaffney · Wellcome Sanger Institute2 papers (2016–2016)Pedro Madrigal · European Bioinformatics Institute2 papers (2016–2016)Ciara H. O’Flanagan · University of North Carolina at Chapel Hill2 papers (2019–2024)Alejandra Cervera · National Institute of Genomic Medicine2 papers (2016–2016)Alayne Brunner · Eunice Kennedy Shriver National Institute of Child Health and Human Development1 papers (2012–2012)Leah Prentice · B.C. Women's Hospital & Health Centre1 papers (2012–2012)