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Daniel Lai

Provincial Health Services Authority ·
Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include Cancer Genomics and Diagnostics, Single-cell and spatial transcriptomics, Epigenetics and DNA Methylation, and Immune Cell Function and Interaction.
h-index
33
citations
7,830
works
104
NIH funding
primary concept
email

Recent publications

Cancer Research in the Age of Spatial Omics: Lessons from IMAXT
Cancer Discovery 2025cited by 4position: middledoi
Ultrasensitive plasma-based monitoring of tumor burden using machine-learning-guided signal enrichment
Nature Medicine 2024cited by 91position: middledoi
Single-cell genomic variation induced by mutational processes in cancer
Nature 2022cited by 151position: middledoi
Three-dimensional imaging mass cytometry for highly multiplexed molecular and cellular mapping of tissues and the tumor microenvironment
Nature Cancer 2021cited by 213position: middledoi
Clonal fitness inferred from time-series modelling of single-cell cancer genomes
Nature 2021cited by 169position: middledoi
Landscapes of cellular phenotypic diversity in breast cancer xenografts and their impact on drug response
Nature Communications 2021cited by 58position: middledoi
Probabilistic cell-type assignment of single-cell RNA-seq for tumor microenvironment profiling
Nature Methods 2019cited by 422position: middledoi
Molecular and Genetic Characterization of MHC Deficiency Identifies EZH2 as Therapeutic Target for Enhancing Immune Recognition
Cancer Discovery 2019cited by 312position: middledoi
Interfaces of Malignant and Immunologic Clonal Dynamics in Ovarian Cancer
Cell 2018cited by 383position: middledoi
CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours
Nature Communications 2017cited by 584position: middledoi
The clonal and mutational evolution spectrum of primary triple-negative breast cancers
Nature 2012cited by 2,019position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

· 1 papers (2019–2019)Christian Steidl · BC Cancer Agency1 papers (2019–2019)Allen W. Zhang · University of British Columbia1 papers (2019–2019)Andrew McPherson · Provincial Health Services Authority1 papers (2019–2019)Elizabeth A. Chavez · Spinal Cord Injury BC1 papers (2019–2019) · 1 papers (2019–2019)Jessica N. McAlpine · BC Cancer Agency1 papers (2019–2019)Andrew P. Weng · Terry Fox Research Institute1 papers (2019–2019)Samuel Aparício · BC Cancer Agency1 papers (2019–2019)Tomohiro Aoki · University of Toronto1 papers (2019–2019)Tim Hon Man Chan · Precigen (United States)1 papers (2019–2019)Lauren C. Chong · BC Cancer Agency1 papers (2019–2019)Anja Mottok · Universität Ulm1 papers (2019–2019)Kieran R. Campbell · Ontario Institute for Cancer Research1 papers (2019–2019) · 1 papers (2019–2019)Ciara H. O’Flanagan · University of North Carolina at Chapel Hill1 papers (2019–2019)Xuehai Wang · Shandong University1 papers (2019–2019)Sohrab P. Shah · Columbia University Irving Medical Center1 papers (2019–2019) · 1 papers (2019–2019)Nicholas Ceglia · Memorial Hospital1 papers (2019–2019)