Area of research
Molecular Biology · Spectroscopy
Research interest
Research interests include RNA and protein synthesis mechanisms, Glycosylation and Glycoproteins Research, Advanced Proteomics Techniques and Applications, and Click Chemistry and Applications.
Immune checkpoint TIM-3 regulates microglia and Alzheimer’s disease
A mutant ASXL1-BAP1-EHMT complex contributes to heterochromatin dysfunction in clonal hematopoiesis and chronic monomyelocytic leukemia
Neuronal activity-driven O-GlcNAcylation promotes mitochondrial plasticity
Post-translational modification-centric base editor screens to assess phosphorylation site functionality in high throughput
OGT controls mammalian cell viability by regulating the proteasome/mTOR/ mitochondrial axis
A biotin targeting chimera (BioTAC) system to map small molecule interactomes in situ
A regulatory circuit controlled by extranuclear and nuclear retinoic acid receptor α determines T cell activation and function
Retron reverse transcriptase termination and phage defense are dependent on host RNase H1
Congenital anemia reveals distinct targeting mechanisms for master transcription factor GATA1
Novel Antibodies for the Simple and Efficient Enrichment of Native O-GlcNAc Modified Peptides
Blockade of IL-22 signaling reverses erythroid dysfunction in stress-induced anemias
RNA–protein interaction mapping via MS2- or Cas13-based APEX targeting
Proteomic Profiling of the ECM of Xenograft Breast Cancer Metastases in Different Organs Reveals Distinct Metastatic Niches
Streamlined Protocol for Deep Proteomic Profiling of FAC-sorted Cells and Its Application to Freshly Isolated Murine Immune Cells*
Trio Haploinsufficiency Causes Neurodevelopmental Disease-Associated Deficits
SMAC mimetics promote NIK-dependent inhibition of CD4 <sup>+</sup> T <sub>H</sub> 17 cell differentiation
Epigenetic resetting of human pluripotency
Antibodies to biotin enable large-scale detection of biotinylation sites on proteins
SOX2 O-GlcNAcylation alters its protein-protein interactions and genomic occupancy to modulate gene expression in pluripotent cells
Human RNA Polymerase II Promoter Recruitment in Vitro Is Regulated by O-Linked N-Acetylglucosaminyltransferase (OGT)
Electron transfer dissociation (<scp>ETD</scp>): The mass spectrometric breakthrough essential for <i><scp>O</scp></i>‐Glc<scp>NA</scp>c protein site assignments—a study of the <i><scp>O</scp></i>‐Glc<scp>NA</scp>cylated protein <scp>H</scp>ost <scp>C</scp>ell <scp>F</scp>actor <scp>C</scp>1
Belmont Forum Collaborative Research: Climate change, pollinator declines and the human diet
Factors Affecting Differential Rates of Prison Incarcera- tion: 1850-Present
Employment Opportunities and Crime
Fourth National Conference on Blacks in Higher Education, April 26-29, 1979, Washington, D.C.