Area of research
Molecular Biology · Materials Chemistry
Research interest
Research interests include Protein Structure and Dynamics, Enzyme Structure and Function, Protein Kinase Regulation and GTPase Signaling, and Computational Drug Discovery Methods.
A dynamic hydrophobic core orchestrates allostery in protein kinases
Mutation of a kinase allosteric node uncouples dynamics linked to phosphotransfer
Decoding the Interactions Regulating the Active State Mechanics of Eukaryotic Protein Kinases
Dynamic architecture of a protein kinase
Synchronous Opening and Closing Motions Are Essential for cAMP-Dependent Protein Kinase A Signaling
Dynamic architecture of a protein kinase (802.22)
Substrate and Inhibitor-induced Dimerization and Cooperativity in Caspase-1 but Not Caspase-3
Comparing Conformational Ensembles Using the Kullback–Leibler Divergence Expansion
Conformational Equilibrium of N-Myristoylated cAMP-Dependent Protein Kinase A by Molecular Dynamics Simulations