Area of research
Surgery · Radiology, Nuclear Medicine and Imaging
Research interest
Research interests include Monoclonal and Polyclonal Antibodies Research, Peptidase Inhibition and Analysis, Bladder and Urothelial Cancer Treatments, and Glycosylation and Glycoproteins Research.
CRISPRi-based screen of autism spectrum disorder risk genes in microglia uncovers roles of ADNP in microglia endocytosis and synaptic pruning
Engineered Proteins and Chemical Tools to Probe the Cell Surface Proteome
Ultrasensitive detection of intact SARS-CoV-2 particles in complex biofluids using microfluidic affinity capture
Hijacking Extracellular Targeted Protein Degrader–Drug Conjugates for Enhanced Drug Delivery
Temporal photoproximity labeling of ligand-activated EGFR neighborhoods using MultiMap
High-affinity CD16A polymorphism associated with reduced risk ofsevere COVID-19
Multiscale photocatalytic proximity labeling reveals cell surface neighbors on and between cells
Oxidative cyclization reagents reveal tryptophan cation–π interactions
Antibody discovery identifies regulatory mechanisms of protein arginine deiminase 4
Transcobalamin receptor antibodies in autoimmune vitamin B12 central deficiency
Mechanism-guided engineering of a minimal biological particle for genome editing
Extracellular targeted protein degradation: an emerging modality for drug discovery
Site-specific proximity labeling at single residue resolution for identification of protein partners <i>in vitro</i> and on cells
Modular cytokine receptor-targeting chimeras for targeted degradation of cell surface and extracellular proteins
Ribosome stalling during selenoprotein translation exposes a ferroptosis vulnerability
The surfaceome of multiple myeloma cells suggests potential immunotherapeutic strategies and protein markers of drug resistance
Roadmap for Optimizing and Broadening Antibody-Based PROTACs for Degradation of Cell Surface Proteins
Cell-surface tethered promiscuous biotinylators enable comparative small-scale surface proteomic analysis of human extracellular vesicles and cells
Targeting a proteolytic neoepitope on CUB domain containing protein 1 (CDCP1) for RAS-driven cancers
MEK inhibition enhances presentation of targetable MHC-I tumor antigens in mutant melanomas
Development of Antibody-Based PROTACs for the Degradation of the Cell-Surface Immune Checkpoint Protein PD-L1
SARS-CoV-2 antibody magnitude and detectability are driven by disease severity, timing, and assay
Engineering luminescent biosensors for point-of-care SARS-CoV-2 antibody detection
The CD28-Transmembrane Domain Mediates Chimeric Antigen Receptor Heterodimerization With CD28
Precision Engineering of an Anti-HLA-A2 Chimeric Antigen Receptor in Regulatory T Cells for Transplant Immune Tolerance
Engineered ACE2 receptor traps potently neutralize SARS-CoV-2
ReScan, a Multiplex Diagnostic Pipeline, Pans Human Sera for SARS-CoV-2 Antigens
Broad and thematic remodeling of the surfaceome and glycoproteome on isogenic cells transformed with driving proliferative oncogenes
Competitive SARS-CoV-2 Serology Reveals Most Antibodies Targeting the Spike Receptor-Binding Domain Compete for ACE2 Binding
Deep profiling of protease substrate specificity enabled by dual random and scanned human proteome substrate phage libraries
SBIR Phase II: Miniature Mass Spectrometer for Liquids Analysis
SBIR Phase I: Miniature Mass Spectrometer for Expired Breath Analysis
A Proposal for Implementing Calculus Reform in West Appalachia
Workshop on Structure and Function of Mutated Proteins; Florence, Italy, August 26-30, 1991.
Acquisition of Mathematical Sciences Research Equipment
Microcomputer Laboratory For Undergraduate Mathematics Instruction