Area of research
Physiology · Genetics
Research interest
Research interests include Telomeres, Telomerase, and Senescence, Glioma Diagnosis and Treatment, Cancer Research and Treatments, and Cancer Cells and Metastasis.
Disruption of stem cell niche–confined R-spondin 3 expression leads to impaired hematopoiesis
Cancer-specific loss of <i>TERT</i> activation sensitizes glioblastoma to DNA damage
Disruption of the β1L Isoform of GABP Reverses Glioblastoma Replicative Immortality in a TERT Promoter Mutation-Dependent Manner
Mutant IDH1 Expression Drives <i>TERT</i> Promoter Reactivation as Part of the Cellular Transformation Process
The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer