Area of research
Molecular Biology · Public Health, Environmental and Occupational Health
Research interest
Research interests include Acute Lymphoblastic Leukemia research, Glioma Diagnosis and Treatment, Chromatin Remodeling and Cancer, and Protein Degradation and Inhibitors.
Bone morphogenetic protein (BMP) signaling determines neuroblastoma cell fate and sensitivity to retinoic acid
Tandem Duplications in <i>UBTF</i> Create XPO1-Dependent Nuclear Export Signals that Reveal a Leukemic Therapeutic Dependency
Capmatinib is an effective treatment for MET-fusion driven pediatric high-grade glioma and synergizes with radiotherapy
Biologic and Clinical Analysis of Childhood Gamma Delta T-ALL Identifies <i>LMO2/STAG2</i> Rearrangements as Extremely High Risk
MODL-06. Targeting c-MET in combination with radiation is effective in MET-fusion driven high-grade glioma
The chemotherapeutic CX-5461 primarily targets TOP2B and exhibits selective activity in high-risk neuroblastoma
Modeling and targeting of erythroleukemia by hematopoietic genome editing
Identification of small molecules that mitigate vincristine‐induced neurotoxicity while sensitizing leukemia cells to vincristine
Rhabdoid Tumors Are Sensitive to the Protein-Translation Inhibitor Homoharringtonine
Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses
Selective modulation of the androgen receptor AF2 domain rescues degeneration in spinal bulbar muscular atrophy
Establishing a Preclinical Multidisciplinary Board for Brain Tumors
Orthotopic patient-derived xenografts of paediatric solid tumours
Simvastatin Hydroxy Acid Fails to Attain Sufficient Central Nervous System Tumor Exposure to Achieve a Cytotoxic Effect: Results of a Preclinical Cerebral Microdialysis Study
Targeting the DNA Repair Pathway in Ewing Sarcoma
Pemetrexed and Gemcitabine as Combination Therapy for the Treatment of Group3 Medulloblastoma
Pharmacokinetics and Efficacy of the Spleen Tyrosine Kinase Inhibitor R406 after Ocular Delivery for Retinoblastoma