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Burgess B. Freeman

Illinois Institute of Technology ·
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Area of research
Molecular Biology · Public Health, Environmental and Occupational Health
Research interest
Research interests include Acute Lymphoblastic Leukemia research, Glioma Diagnosis and Treatment, Chromatin Remodeling and Cancer, and Protein Degradation and Inhibitors.
h-index
25
citations
2,489
works
196
NIH funding
primary concept
Medicine
email

Recent publications

Bone morphogenetic protein (BMP) signaling determines neuroblastoma cell fate and sensitivity to retinoic acid
Nature Communications 2025cited by 4position: middledoi
Tandem Duplications in <i>UBTF</i> Create XPO1-Dependent Nuclear Export Signals that Reveal a Leukemic Therapeutic Dependency
Blood Cancer Discovery 2025cited by 1position: middledoi
Capmatinib is an effective treatment for MET-fusion driven pediatric high-grade glioma and synergizes with radiotherapy
Molecular Cancer 2024cited by 17position: middledoi
Biologic and Clinical Analysis of Childhood Gamma Delta T-ALL Identifies <i>LMO2/STAG2</i> Rearrangements as Extremely High Risk
Cancer Discovery 2024cited by 13position: middledoi
MODL-06. Targeting c-MET in combination with radiation is effective in MET-fusion driven high-grade glioma
Neuro-Oncology 2022cited by 3position: middledoi
The chemotherapeutic CX-5461 primarily targets TOP2B and exhibits selective activity in high-risk neuroblastoma
Nature Communications 2021cited by 90position: middledoi
Modeling and targeting of erythroleukemia by hematopoietic genome editing
Blood 2021cited by 43position: middledoi
Identification of small molecules that mitigate vincristine‐induced neurotoxicity while sensitizing leukemia cells to vincristine
Clinical and Translational Science 2021cited by 17position: middledoi
Rhabdoid Tumors Are Sensitive to the Protein-Translation Inhibitor Homoharringtonine
Clinical Cancer Research 2020cited by 24position: middledoi
Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses
Cancer Cell 2018cited by 165position: middledoi
Selective modulation of the androgen receptor AF2 domain rescues degeneration in spinal bulbar muscular atrophy
Nature Medicine 2018cited by 44position: middledoi
Establishing a Preclinical Multidisciplinary Board for Brain Tumors
Clinical Cancer Research 2018cited by 19position: middledoi
Orthotopic patient-derived xenografts of paediatric solid tumours
Nature 2017cited by 303position: middledoi
Simvastatin Hydroxy Acid Fails to Attain Sufficient Central Nervous System Tumor Exposure to Achieve a Cytotoxic Effect: Results of a Preclinical Cerebral Microdialysis Study
Drug Metabolism and Disposition 2016cited by 3position: middledoi
Targeting the DNA Repair Pathway in Ewing Sarcoma
Cell Reports 2014cited by 180position: middledoi
Pemetrexed and Gemcitabine as Combination Therapy for the Treatment of Group3 Medulloblastoma
Cancer Cell 2014cited by 146position: middledoi
Pharmacokinetics and Efficacy of the Spleen Tyrosine Kinase Inhibitor R406 after Ocular Delivery for Retinoblastoma
Pharmaceutical Research 2014cited by 26position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Anang A. Shelat · University of Kentucky5 papers (2014–2021) · 4 papers (2014–2020) · 3 papers (2014–2017)Michael A. Dyer · Phoenix Contact (United States)3 papers (2014–2017)R. Kiplin Guy · University of Kentucky2 papers (2014–2014) · 2 papers (2014–2014)Jianrong Wu · University of Kentucky2 papers (2014–2017)Brittney Gordon · George Washington University2 papers (2014–2017) · 2 papers (2014–2017)Nidal Boulos · Cancer Research UK Cambridge Center2 papers (2016–2018)Armita Bahrami · Emory University2 papers (2014–2017) · 2 papers (2017–2018)Åsa Karlström · St. Jude Children's Research Hospital2 papers (2014–2017)Richard J. Gilbertson · University of Cambridge2 papers (2016–2018)Pradeep K. Vuppala · Cancer Research UK Cambridge Center2 papers (2016–2018)Yingzhe Wang · St. Jude Children's Research Hospital2 papers (2018–2021) · 2 papers (2017–2020)Martine F. Roussel · University of Kentucky2 papers (2014–2018)David C. Turner · American Academy of Pediatrics2 papers (2014–2016)Megan O. Jacus · Cancer Research UK Cambridge Center2 papers (2014–2016)
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