Area of research
Molecular Biology · Oncology
Research interest
Research interests include DNA Repair Mechanisms, CRISPR and Genetic Engineering, Cell death mechanisms and regulation, and Cancer-related Molecular Pathways.
The Fanconi anemia core complex promotes CtIP-dependent end resection to drive homologous recombination at DNA double-strand breaks
An atlas of substrate specificities for the human serine/threonine kinome
FIRRM/C1orf112 is synthetic lethal with PICH and mediates RAD51 dynamics
Multi-pathway DNA-repair reporters reveal competition between end-joining, single-strand annealing and homologous recombination at Cas9-induced DNA double-strand breaks
ROS and Oxidative Stress Are Elevated in Mitosis during Asynchronous Cell Cycle Progression and Are Exacerbated by Mitotic Arrest
Comprehensive profiling of the STE20 kinase family defines features essential for selective substrate targeting and signaling output
Comprehensive substrate specificity profiling of the human Nek kinome reveals unexpected signaling outputs
Proteasome Activation by Small Molecules
Limited Mitochondrial Permeabilization Causes DNA Damage and Genomic Instability in the Absence of Cell Death