Area of research
Hematology · Molecular Biology
Research interest
Research interests include Acute Myeloid Leukemia Research, Acute Lymphoblastic Leukemia research, Protein Degradation and Inhibitors, and RNA modifications and cancer.
Multiselective RAS(ON) inhibition targets oncogenic RAS and overcomes RAS-mediated resistance to FLT3i and BCL2i in AML
Hematopoietic Stem Cell Transplantation Outcomes for High-Risk AML: A Report From the Children's Oncology Group
Multi-omic single cell sequencing reveals discordant MRD and mechanisms of relapse in pediatric AML
A new genomic framework to categorize pediatric acute myeloid leukemia
Targeting Ras-, Rho-, and Rab-family GTPases via a conserved cryptic pocket
<i>In Vivo</i> and <i>In Vitro</i> Chemical Synthetic Lethality of ABHD17 and MEK Inhibition in <i>NRAS</i>-Mutant Acute Myeloid Leukemia
Etiology of oncogenic fusions in 5,190 childhood cancers and its clinical and therapeutic implication
Structural surfaceomics reveals an AML-specific conformation of integrin β2 as a CAR T cellular therapy target
Framework humanization optimizes potency of anti-CD72 nanobody CAR-T cells for B-cell malignancies
Melanoma in infants, caused by a gene fusion involving the anaplastic lymphoma kinase (<scp>ALK)</scp>
Integrated stem cell signature and cytomolecular risk determination in pediatric acute myeloid leukemia
CBFA2T3-GLIS2 model of pediatric acute megakaryoblastic leukemia identifies FOLR1 as a CAR T cell target
ABHD17 regulation of plasma membrane palmitoylation and N-Ras-dependent cancer growth
Genetic disruption of N-RasG12D palmitoylation perturbs hematopoiesis and prevents myeloid transformation in mice
Glucocorticoids paradoxically facilitate steroid resistance in T cell acute lymphoblastic leukemias and thymocytes
KRAS Allelic Imbalance Enhances Fitness and Modulates MAP Kinase Dependence in Cancer
JAK/STAT pathway inhibition overcomes IL7-induced glucocorticoid resistance in a subset of human T-cell acute lymphoblastic leukemias