Area of research
Organic Chemistry · Oncology
Research interest
Research interests include Click Chemistry and Applications, Peptidase Inhibition and Analysis, Protein Kinase Regulation and GTPase Signaling, and Adenosine and Purinergic Signaling.
A proteome-wide atlas of lysine-reactive chemistry
ABHD17 regulation of plasma membrane palmitoylation and N-Ras-dependent cancer growth
An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells
Genetic disruption of N-RasG12D palmitoylation perturbs hematopoiesis and prevents myeloid transformation in mice
Notum produced by Paneth cells attenuates regeneration of aged intestinal epithelium
A Pan-ALDH1A Inhibitor Induces Necroptosis in Ovarian Cancer Stem-like Cells
Chemical Proteomics Identifies Druggable Vulnerabilities in a Genetically Defined Cancer