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Spencer C. Peck

Pfizer (United States) · US
Area of research
Inorganic Chemistry · Renewable Energy, Sustainability and the Environment
Research interest
Research interests include Metal-Catalyzed Oxygenation Mechanisms, Metalloenzymes and iron-sulfur proteins, Biochemical and Molecular Research, and Folate and B Vitamins Research.
h-index
14
citations
857
works
23
NIH funding
primary concept
email

Recent publications

Use of the dehydrophos biosynthetic enzymes to prepare antimicrobial analogs of alaphosphin
Organic & Biomolecular Chemistry 2018cited by 8position: middledoi
A prominent glycyl radical enzyme in human gut microbiomes metabolizes <i>trans</i> -4-hydroxy- <scp>l</scp> -proline
Science 2017cited by 143position: middledoi
Structural basis for methylphosphonate biosynthesis
Science 2017cited by 59position: middledoi
O–H Activation by an Unexpected Ferryl Intermediate during Catalysis by 2-Hydroxyethylphosphonate Dioxygenase
Journal of the American Chemical Society 2017cited by 39position: firstdoi
Go it alone: four-electron oxidations by mononuclear non-heme iron enzymes
JBIC Journal of Biological Inorganic Chemistry 2016cited by 47position: firstdoi
Oxygen-18 Kinetic Isotope Effects of Nonheme Iron Enzymes HEPD and MPnS Support Iron(III) Superoxide as the Hydrogen Abstraction Species
Journal of the American Chemical Society 2015cited by 43position: middledoi
A Common Late-Stage Intermediate in Catalysis by 2-Hydroxyethyl-phosphonate Dioxygenase and Methylphosphonate Synthase
Journal of the American Chemical Society 2015cited by 24position: firstdoi
Phosphonate biosynthesis and catabolism: a treasure trove of unusual enzymology
Current Opinion in Chemical Biology 2013cited by 75position: firstdoi
Structure and Function of Phosphonoacetaldehyde Dehydrogenase: The Missing Link in Phosphonoacetate Formation
Chemistry & Biology 2013cited by 32position: middledoi
Mechanistic Investigation of Methylphosphonate Synthase, a Non-Heme Iron-Dependent Oxygenase
Journal of the American Chemical Society 2012cited by 27position: middledoi
Discovery and Biosynthesis of Phosphonate and Phosphinate Natural Products
Methods in enzymology on CD-ROM/Methods in enzymology 2012cited by 27position: firstdoi
Stereochemistry of hydride transfer by group III alcohol dehydrogenases involved in phosphonate biosynthesis
MedChemComm 2012cited by 6position: firstdoi

Grants

No grants ingested yet.

Frequent collaborators

Wilfred A. van der Donk · Howard Hughes Medical Institute11 papers (2012–2018)Satish K. Nair · University of Illinois Urbana-Champaign2 papers (2013–2015)Jonathan R. Chekan · University of North Carolina at Greensboro2 papers (2013–2015)Bradley S. Evans · South Australia Pathology2 papers (2012–2012)Emily C. Ulrich · IIT@MIT2 papers (2015–2017)Yolanda Y. Huang · Lawrence Berkeley National Laboratory1 papers (2017–2017)Laura M. K. Dassama · Pennsylvania State University1 papers (2017–2017)Eric A. Franzosa · Harvard University1 papers (2017–2017)Judith P. Klinman · University of California, Berkeley1 papers (2015–2015)Chi P. Ting · University of California, Berkeley1 papers (2018–2018)Emily P. Balskus · Howard Hughes Medical Institute1 papers (2017–2017)Catherine L. Drennan · Howard Hughes Medical Institute1 papers (2017–2017)J. Martin Bollinger · Massachusetts Institute of Technology1 papers (2017–2017)Jui-Hui Chen · University of Illinois Urbana-Champaign1 papers (2013–2013)Seung Young Kim · University of Illinois Urbana-Champaign1 papers (2012–2012)Lauren J. Rajakovich · Pennsylvania State University1 papers (2017–2017)Bo Zhang · Pennsylvania State University1 papers (2017–2017)Chen Wang · Ministry of Education of the People's Republic of China1 papers (2017–2017)Hui Zhu · National University of Singapore1 papers (2015–2015)Yifeng Wei · Massachusetts Institute of Technology1 papers (2017–2017)