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Paula Desplats

University of California San Diego · US
Area of research
Neurology · Cellular and Molecular Neuroscience
Research interest
Research interests include Parkinson's Disease Mechanisms and Treatments, Alzheimer's disease research and treatments, Epigenetics and DNA Methylation, and Nerve injury and regeneration.
h-index
43
citations
8,873
works
87
NIH funding
primary concept
email

Recent publications

Control of innate olfactory valence by segregated cortical amygdala circuits
eLife 2025cited by 3position: middledoi
Circadian modulation by time-restricted feeding rescues brain pathology and improves memory in mouse models of Alzheimer’s disease
Cell Metabolism 2023cited by 131position: lastdoi
Common Variants Near <scp>ZIC1</scp> and <scp>ZIC4</scp> in Autopsy‐Confirmed Multiple System Atrophy
Movement Disorders 2022cited by 15position: middledoi
Perfect timing: circadian rhythms, sleep, and immunity — an NIH workshop summary
JCI Insight 2020cited by 246position: middledoi
Evaluation of Biochemical and Epigenetic Measures of Peripheral Brain-Derived Neurotrophic Factor (BDNF) as a Biomarker in Huntington’s Disease Patients
Frontiers in Molecular Neuroscience 2020cited by 58position: lastdoi
DNA methylation changes associated with Parkinson’s disease progression: outcomes from the first longitudinal genome-wide methylation analysis in blood
Epigenetics 2019cited by 90position: lastdoi
Microglial memory of early life stress and inflammation: Susceptibility to neurodegeneration in adulthood
Neuroscience & Biobehavioral Reviews 2019cited by 67position: firstdoi
A <i>de novo</i> compound targeting α-synuclein improves deficits in models of Parkinson's disease
Brain 2016cited by 156position: middledoi
Circadian alterations during early stages of Alzheimer's disease are associated with aberrant cycles of DNA methylation in BMAL1
Alzheimer s & Dementia 2016cited by 147position: lastdoi
RETRACTED: ESCRT-mediated Uptake and Degradation of Brain-targeted α-synuclein Single Chain Antibody Attenuates Neuronal Degeneration In Vivo
Molecular Therapy 2014cited by 82position: middledoi
RETRACTED ARTICLE: Hippocampal neuronal cells that accumulate α-synuclein fragments are more vulnerable to Aβ oligomer toxicity via mGluR5 – implications for dementia with Lewy bodies
Molecular Neurodegeneration 2014cited by 76position: middledoi
Distinctive patterns of DNA methylation associated with Parkinson disease
Epigenetics 2013cited by 324position: lastdoi
TOM40 Mediates Mitochondrial Dysfunction Induced by α-Synuclein Accumulation in Parkinson’s Disease
PLoS ONE 2013cited by 152position: middledoi
Antibody-Aided Clearance of Extracellular α-Synuclein Prevents Cell-to-Cell Aggregate Transmission
Journal of Neuroscience 2012cited by 332position: middledoi
Role of α‐synuclein penetration into the membrane in the mechanisms of oligomer pore formation
FEBS Journal 2012cited by 173position: middledoi
Combined exposure to Maneb and Paraquat alters transcriptional regulation of neurogenesis-related genes in mice models of Parkinson’s disease
Molecular Neurodegeneration 2012cited by 83position: firstdoi
α-Synuclein Induces Alterations in Adult Neurogenesis in Parkinson Disease Models via p53-mediated Repression of Notch1
Journal of Biological Chemistry 2012cited by 75position: firstdoi

Grants

No grants ingested yet.

Frequent collaborators

Eliezer Masliah · Institute on Aging10 papers (2012–2016)Edward Rockenstein · University of California San Diego6 papers (2012–2016)Brian Spencer · University of Southern California6 papers (2012–2016)Christina Patrick · University of California San Diego4 papers (2012–2014)Kori Kosberg · University of California System3 papers (2012–2014)Simona Eleuteri · Harvard University2 papers (2014–2016)Wolfgang Wrasidlo · University of California San Diego2 papers (2012–2016)Anthony Adame · University of California, San Diego2 papers (2013–2014)Cassia Overk · University of California San Diego2 papers (2014–2016)Haylie Romero · University of California San Diego2 papers (2023–2025)Leslie Crews · University of California San Diego2 papers (2012–2012)Michael Mante · University of California San Diego2 papers (2012–2013)Igor F. Tsigelny · San Diego Supercomputer Center2 papers (2012–2016)Tania Gonzalez · Universidad Central2 papers (2012–2014)Ashley Gutierrez · Broad Institute2 papers (2019–2020) · 2 papers (2014–2016)Douglas Galasko · University of California, San Diego1 papers (2013–2013)Pruthul Pathel · University of California San Diego1 papers (2012–2012)Yvonne Lee · Northwestern University1 papers (2020–2020)Aric A. Prather · University of California, San Francisco1 papers (2020–2020)