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Julie Kobie

Merck & Co., Inc., Rahway, NJ, USA (United States) · US
Area of research
Oncology · Pulmonary and Respiratory Medicine
Research interest
Research interests include Cancer Immunotherapy and Biomarkers, Lung Cancer Treatments and Mutations, Gastric Cancer Management and Outcomes, and Pancreatic and Hepatic Oncology Research.
h-index
21
citations
1,758
works
78
NIH funding
primary concept
Medicine
email

Recent publications

Four-year outcomes and circulating tumor DNA (ctDNA) analysis of pembrolizumab (pembro) plus concurrent chemoradiation therapy (cCRT) in unresectable, locally advanced, stage III non–small-cell lung cancer (NSCLC): From KEYNOTE-799.
Journal of Clinical Oncology 2024cited by 5position: middledoi
Associations of tissue tumor mutational burden and mutational status with clinical outcomes in KEYNOTE-042: pembrolizumab versus chemotherapy for advanced PD-L1-positive NSCLC
Annals of Oncology 2023cited by 69position: middledoi
Biomarker-directed, pembrolizumab-based combination therapy in non-small cell lung cancer: phase 2 KEYNOTE-495/KeyImPaCT trial interim results
Nature Medicine 2023cited by 44position: middledoi
Association of Tumor Mutational Burden with Efficacy of Pembrolizumab±Chemotherapy as First-Line Therapy for Gastric Cancer in the Phase III KEYNOTE-062 Study
Clinical Cancer Research 2022cited by 88position: middledoi
Associations of Tissue Tumor Mutational Burden and Mutational Status With Clinical Outcomes With Pembrolizumab Plus Chemotherapy Versus Chemotherapy For Metastatic NSCLC
JTO Clinical and Research Reports 2022cited by 41position: middledoi
Five Year Survival Update From KEYNOTE-010: Pembrolizumab Versus Docetaxel for Previously Treated, Programmed Death-Ligand 1–Positive Advanced NSCLC
Journal of Thoracic Oncology 2021cited by 307position: middledoi
Transcriptomic Determinants of Response to Pembrolizumab Monotherapy across Solid Tumor Types
Clinical Cancer Research 2021cited by 73position: middledoi
Molecular determinants of clinical outcomes with pembrolizumab versus paclitaxel in a randomized, open-label, phase III trial in patients with gastroesophageal adenocarcinoma
Annals of Oncology 2021cited by 67position: middledoi
The association of tissue tumor mutational burden (tTMB) using the Foundation Medicine genomic platform with efficacy of pembrolizumab versus paclitaxel in patients (pts) with gastric cancer (GC) from KEYNOTE-061.
Journal of Clinical Oncology 2020cited by 54position: middledoi
Abstract CT084: Relationship between <i>STK11</i> and <i>KEAP1</i> mutational status and efficacy in KEYNOTE-042: pembrolizumab monotherapy versus platinum-based chemotherapy as first-line therapy for PD-L1-positive advanced NSCLC
Cancer Research 2020cited by 43position: middledoi
The association of molecular biomarkers with efficacy of pembrolizumab versus paclitaxel in patients with gastric cancer (GC) from KEYNOTE-061.
Journal of Clinical Oncology 2020cited by 32position: middledoi
Pembrolizumab (pembro) plus platinum-based chemotherapy (chemo) for metastatic NSCLC: Tissue TMB (tTMB) and outcomes in KEYNOTE-021, 189, and 407
Annals of Oncology 2019cited by 104position: middledoi
Association between tissue TMB (tTMB) and clinical outcomes with pembrolizumab monotherapy (pembro) in PD-L1-positive advanced NSCLC in the KEYNOTE-010 and -042 trials
Annals of Oncology 2019cited by 100position: middledoi
OA04.06 Evaluation of TMB in KEYNOTE-189: Pembrolizumab Plus Chemotherapy vs Placebo Plus Chemotherapy for Nonsquamous NSCLC
Journal of Thoracic Oncology 2019cited by 93position: middledoi
LBA4 Association of KRAS mutational status with response to pembrolizumab monotherapy given as first-line therapy for PD-L1-positive advanced non-squamous NSCLC in Keynote-042
Annals of Oncology 2019cited by 92position: middledoi
KRAS mutational status and efficacy in KEYNOTE-189: Pembrolizumab (pembro) plus chemotherapy (chemo) vs placebo plus chemo as first-line therapy for metastatic non-squamous NSCLC
Annals of Oncology 2019cited by 82position: middledoi
OA04.05 KEYNOTE-021: TMB and Outcomes for Carboplatin and Pemetrexed With or Without Pembrolizumab for Nonsquamous NSCLC
Journal of Thoracic Oncology 2019cited by 64position: middledoi
Genetic sharing and heritability of paediatric age of onset autoimmune diseases
Nature Communications 2015cited by 80position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Răzvan Cristescu · Merck & Co., Inc., Rahway, NJ, USA (United States)15 papers (2019–2023)Deepti Aurora-Garg · Merck & Co., Inc., Rahway, NJ, USA (United States)13 papers (2019–2023)Jared Lunceford · Merck & Co., Inc., Rahway, NJ, USA (United States)10 papers (2019–2023)Mark Ayers · Merck & Co., Inc., Rahway, NJ, USA (United States)10 papers (2019–2023)Bilal Piperdi · Merck & Co., Inc., Rahway, NJ, USA (United States)10 papers (2019–2023)Andrey Loboda · Merck & Co., Inc., Rahway, NJ, USA (United States)8 papers (2019–2023)M. Catherine Pietanza · Merck & Co., Inc., Rahway, NJ, USA (United States)8 papers (2019–2023)Edward B. Garon · Cancer Clinic5 papers (2019–2023) · 5 papers (2019–2021)Roy S. Herbst · Yale New Haven Hospital5 papers (2019–2023)Shirish M. Gadgeel · The Barbara Ann Karmanos Cancer Institute5 papers (2019–2022)Byoung Chul Cho · Université Grenoble Alpes4 papers (2019–2023)Tony Mok · South China University of Technology4 papers (2019–2023)Dariusz M. Kowalski · National Institute of Oncology4 papers (2019–2024)Gilberto de Castro · Twitter (United States)4 papers (2019–2023)Enriqueta Felip · Université Grenoble Alpes4 papers (2019–2023)Eric Van Cutsem · KU Leuven4 papers (2020–2022)Marina Chiara Garassino · Comprehensive Cardiovascular4 papers (2019–2022)Z. Alexander Cao · Wenzhou University4 papers (2020–2022)Rina Hui · The University of Sydney4 papers (2019–2022)