Area of research
Immunology · Radiology, Nuclear Medicine and Imaging
Research interest
Research interests include Monoclonal and Polyclonal Antibodies Research, T-cell and B-cell Immunology, Immune Response and Inflammation, and Immune Cell Function and Interaction.
Phosphotyrosine-mediated LAT assembly on membranes drives kinetic bifurcation in recruitment dynamics of the Ras activator SOS
An electrostatic selection mechanism controls sequential kinase signaling downstream of the T cell receptor
Identification of Inhibitors of the Association of ZAP-70 with the T Cell Receptor by High-Throughput Screen
Modification by covalent reaction or oxidation of cysteine residues in the tandem-SH2 domains of ZAP-70 and Syk can block phosphopeptide binding
Structural Basis for Activation of ZAP-70 by Phosphorylation of the SH2-Kinase Linker