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Long Cai

California Institute of Technology · US
Area of research
Molecular Biology · Biophysics
Research interest
Research interests include Single-cell and spatial transcriptomics, Cell Image Analysis Techniques, Genomics and Chromatin Dynamics, and RNA Research and Splicing.
h-index
41
citations
17,738
works
111
NIH funding
primary concept
email

Recent publications

Spatial multi-omics reveals cell-type-specific nuclear compartments
Nature 2025cited by 41position: lastdoi
A spatiotemporal atlas of mouse gastrulation and early organogenesis to explore axial patterning and project in vitro models onto in vivo space
Cell Reports 2025cited by 6position: middledoi
Advances and prospects for the Human BioMolecular Atlas Program (HuBMAP)
Nature Cell Biology 2023cited by 168position: middledoi
YTH Domain Proteins Play an Essential Role in Rice Growth and Stress Response
Plants 2022cited by 23position: middledoi
The N6-methyladenosine binding proteins YTH03/05/10 coordinately regulate rice plant height
Plant Science 2022cited by 17position: firstdoi
Giotto: a toolbox for integrative analysis and visualization of spatial expression data
Genome biology 2021cited by 930position: middledoi
Integrated spatial genomics reveals global architecture of single nuclei
Nature 2021cited by 434position: lastdoi
Integration of spatial and single-cell transcriptomic data elucidates mouse organogenesis
Nature Biotechnology 2021cited by 347position: middledoi
Imaging cell lineage with a synthetic digital recording system
Science 2021cited by 147position: middledoi
Single cell biology—a Keystone Symposia report
Annals of the New York Academy of Sciences 2021cited by 4position: middledoi
Transcriptome-scale super-resolved imaging in tissues by RNA seqFISH+
Nature 2019cited by 1,786position: lastdoi
The human body at cellular resolution: the NIH Human Biomolecular Atlas Program
Nature 2019cited by 662position: middledoi
Multimodal Analysis of Cell Types in a Hypothalamic Node Controlling Social Behavior
Cell 2019cited by 274position: middledoi
In situ readout of DNA barcodes and single base edits facilitated by in vitro transcription
Nature Biotechnology 2019cited by 101position: middledoi
Higher-Order Inter-chromosomal Hubs Shape 3D Genome Organization in the Nucleus
Cell 2018cited by 943position: middledoi
The adult human testis transcriptional cell atlas
Cell Research 2018cited by 768position: middledoi
Dynamics and Spatial Genomics of the Nascent Transcriptome by Intron seqFISH
Cell 2018cited by 355position: lastdoi
Identification of spatially associated subpopulations by combining scRNAseq and sequential fluorescence in situ hybridization data
Nature Biotechnology 2018cited by 290position: middledoi
Challenges and emerging directions in single-cell analysis
Genome biology 2017cited by 362position: middledoi
seqFISH Accurately Detects Transcripts in Single Cells and Reveals Robust Spatial Organization in the Hippocampus
Neuron 2017cited by 148position: lastdoi
Profiling the transcriptome with RNA SPOTs
Nature Methods 2017cited by 115position: lastdoi
Multiplexed Dynamic Imaging of Genomic Loci by Combined CRISPR Imaging and DNA Sequential FISH
Biophysical Journal 2017cited by 85position: lastdoi
In Situ Transcription Profiling of Single Cells Reveals Spatial Organization of Cells in the Mouse Hippocampus
Neuron 2016cited by 771position: lastdoi
Synthetic recording and in situ readout of lineage information in single cells
Nature 2016cited by 463position: lastdoi
Single-molecule RNA detection at depth by hybridization chain reaction and tissue hydrogel embedding and clearing
Development 2016cited by 227position: lastdoi
Combinatorial gene regulation by modulation of relative pulse timing
Nature 2015cited by 127position: middledoi
Single-Cell Phenotyping within Transparent Intact Tissue through Whole-Body Clearing
Cell 2014cited by 970position: middledoi
Dynamic Heterogeneity and DNA Methylation in Embryonic Stem Cells
Molecular Cell 2014cited by 320position: middledoi
Pulsatile Dynamics in the Yeast Proteome
Current Biology 2014cited by 79position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Sheel Shah · APLA Health10 papers (2014–2021)Yodai Takei · California Institute of Technology7 papers (2017–2025)Michael B. Elowitz · California Institute of Technology7 papers (2014–2021)Noushin Koulena · California Institute of Technology6 papers (2018–2025)Chee-Huat Linus Eng · California Institute of Technology5 papers (2017–2021)Jina Yun · California Institute of Technology5 papers (2018–2025)Eric Lubeck · California Institute of Technology5 papers (2014–2018)Nico Pierson · California Institute of Technology5 papers (2019–2025)Guo‐Cheng Yuan · Tisch Hospital5 papers (2017–2021)Wen Zhou · California Institute of Technology3 papers (2016–2018)Qian Zhu · Qinghai University3 papers (2018–2021)Ruben Dries · Boston Medical Center3 papers (2018–2021)Mark W. Budde · California Institute of Technology3 papers (2016–2021)Mitchell Guttman · University of California San Diego3 papers (2018–2025)Kirsten L. Frieda · California Institute of Technology2 papers (2016–2021)Noah Ollikainen · National Institute on Aging2 papers (2018–2021)Prashant Bhat · California Institute of Technology2 papers (2018–2025)Jonathan A. Griffiths · European Bioinformatics Institute2 papers (2021–2025)Chiraj K. Dalal · University of California, San Francisco2 papers (2014–2015)Shila Ghazanfar · The University of Sydney2 papers (2021–2025)