Area of research
Molecular Biology · Pulmonary and Respiratory Medicine
Research interest
Research interests include RNA and protein synthesis mechanisms, RNA Research and Splicing, Genomics and Chromatin Dynamics, and CRISPR and Genetic Engineering.
Spatial multi-omics reveals cell-type-specific nuclear compartments
Mapping and engineering RNA-driven architecture of the multiphase nucleolus
An integrated view of the structure and function of the human 4D nucleome
Genome organization around nuclear speckles drives mRNA splicing efficiency
SPRITE: a genome-wide method for mapping higher-order 3D interactions in the nucleus using combinatorial split-and-pool barcoding
Interplay Between Duration of Androgen Deprivation Therapy and External Beam Radiotherapy With or Without a Brachytherapy Boost for Optimal Treatment of High-risk Prostate Cancer
Simultaneous mapping of 3D structure and nascent RNAs argues against nuclear compartments that preclude transcription
RNA promotes the formation of spatial compartments in the nucleus
Nuclear compartmentalization as a mechanism of quantitative control of gene expression
Performance of a Prostate-Specific Membrane Antigen Positron Emission Tomography/Computed Tomography–Derived Risk-Stratification Tool for High-risk and Very High-risk Prostate Cancer
Comparison of Multimodal Therapies and Outcomes Among Patients With High-Risk Prostate Cancer With Adverse Clinicopathologic Features
SARS-CoV-2 Disrupts Splicing, Translation, and Protein Trafficking to Suppress Host Defenses
Higher-Order Inter-chromosomal Hubs Shape 3D Genome Organization in the Nucleus
Surveillance and Processing of Foreign DNA by the Escherichia coli CRISPR-Cas System
CasA mediates Cas3-catalyzed target degradation during CRISPR RNA-guided interference