Area of research
Molecular Biology · Plant Science
Research interest
Research interests include CRISPR and Genetic Engineering, Chromosomal and Genetic Variations, Genomics and Phylogenetic Studies, and RNA and protein synthesis mechanisms.
Randomizing the human genome by engineering recombination between repeat elements
Multiplex generation and single-cell analysis of structural variants in mammalian genomes
Chromothripsis and ecDNA initiated by N4BP2 nuclease fragmentation of cytoplasm-exposed chromosomes
Degradation of GSPT1 causes TP53-independent cell death in leukemia while sparing normal hematopoietic stem cells
BTBBCL6 dimers as building blocks for reversible drug-induced protein oligomerization
The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K
Small-molecule-induced polymerization triggers degradation of BCL6
Selection of Oncogenic Mutant Clones in Normal Human Skin Varies with Body Site
Loss of Neurological Disease HSAN-I-Associated Gene SPTLC2 Impairs CD8+ T Cell Responses to Infection by Inhibiting T Cell Metabolic Fitness