Area of research
Molecular Biology · Radiology, Nuclear Medicine and Imaging
Research interest
Research interests include Effects of Radiation Exposure, DNA Repair Mechanisms, Epigenetics and DNA Methylation, and CRISPR and Genetic Engineering.
The DNA Cytosine Deaminase APOBEC3B is a Molecular Determinant of Platinum Responsiveness in Clear Cell Ovarian Cancer
A panel of eGFP reporters for single base editing by APOBEC-Cas9 editosome complexes
The deaminase APOBEC3B triggers the death of cells lacking uracil DNA glycosylase
HIV-1 Vif Triggers Cell Cycle Arrest by Degrading Cellular PPP2R5 Phospho-regulators
Polyomavirus T Antigen Induces <i>APOBEC3B</i> Expression Using an LXCXE-Dependent and TP53-Independent Mechanism
A fluorescent reporter for quantification and enrichment of DNA editing by APOBEC–Cas9 or cleavage by Cas9 in living cells
A lentivirus-based system for Cas9/gRNA expression and subsequent removal by Cre-mediated recombination
Elevated APOBEC3B expression drives a kataegic-like mutation signature and replication stress-related therapeutic vulnerabilities in p53-defective cells