Area of research
Molecular Biology · Neurology
Research interest
Research interests include Genomics and Phylogenetic Studies, Amyotrophic Lateral Sclerosis Research, Chromosomal and Genetic Variations, and RNA Research and Splicing.
TDP-43 loss induces cryptic polyadenylation in ALS/FTD
Systematic assessment of long-read RNA-seq methods for transcript identification and quantification
PolyGR and polyPR knock-in mice reveal a conserved neuroprotective extracellular matrix signature in C9orf72 ALS/FTD neurons
TDP-43 loss induces extensive cryptic polyadenylation in ALS/FTD
The complete sequence of a human Y chromosome
Accurate isoform discovery with IsoQuant using long reads
The complete sequence of a human genome
Complete genomic and epigenetic maps of human centromeres
Single-nuclei isoform RNA sequencing unlocks barcoded exon connectivity in frozen brain tissue
Chasing perfection: validation and polishing strategies for telomere-to-telomere genome assemblies
The structure, function and evolution of a complete human chromosome 8
TandemTools: mapping long reads and assessing/improving assembly quality in extra-long tandem repeats
MetaMiner: A Scalable Peptidogenomics Approach for Discovery of Ribosomal Peptide Natural Products with Blind Modifications from Microbial Communities
Dereplication of microbial metabolites through database search of mass spectra
Increased diversity of peptidic natural products revealed by modification-tolerant database search of mass spectra
Dereplication of peptidic natural products through database search of mass spectra