Area of research
Molecular Biology · Aging
Research interest
Research interests include Genetics, Aging, and Longevity in Model Organisms, Mitochondrial Function and Pathology, DNA Repair Mechanisms, and Adipose Tissue and Metabolism.
Open problems in ageing science: a roadmap for biogerontology
Innovations in aging biology: highlights from the ARDD emerging science & technologies workshop
Disagreement on foundational principles of biological aging
Spatial mapping of cellular senescence: emerging challenges and opportunities
Nuclear morphology is a deep learning biomarker of cellular senescence
NIH SenNet Consortium to map senescent cells throughout the human lifespan to understand physiological health
High-confidence cancer patient stratification through multiomics investigation of DNA repair disorders
Longevity medicine: upskilling the physicians of tomorrow
Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages
ARDD 2020: from aging mechanisms to interventions
Blood Biochemistry Analysis to Detect Smoking Status and Quantify Accelerated Aging in Smokers
Lamin A/C promotes DNA base excision repair
Latest advances in aging research and drug discovery
Population Specific Biomarkers of Human Aging: A Big Data Study Using South Korean, Canadian, and Eastern European Patient Populations
Vive la radiorésistance!: converging research in radiobiology and biogerontology to enhance human radioresistance for deep space exploration and colonization
NAD + Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair
Effects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice
Nuclear DNA damage signalling to mitochondria in ageing
3‐Hydroxybutyrate regulates energy metabolism and induces <scp>BDNF</scp> expression in cerebral cortical neurons
Defective Mitophagy in XPA via PARP-1 Hyperactivation and NAD+/SIRT1 Reduction
A High-Fat Diet and NAD + Activate Sirt1 to Rescue Premature Aging in Cockayne Syndrome
<scp>SRT</scp>2104 extends survival of male mice on a standard diet and preserves bone and muscle mass
Di-(2-ethylhexyl) phthalate inhibits DNA replication leading to hyperPARylation, SIRT1 attenuation and mitochondrial dysfunction in the testis
Metformin improves healthspan and lifespan in mice