Area of research
Physiology · Cellular and Molecular Neuroscience
Research interest
Research interests include Alzheimer's disease research and treatments, Neuroscience and Neuropharmacology Research, Neuroinflammation and Neurodegeneration Mechanisms, and Mitochondrial Function and Pathology.
International consensus on fasting terminology
Time-Restricted Feeding Reduces Atherosclerosis in LDLR KO Mice but Not in ApoE Knockout Mice
Common and divergent molecular mechanisms of fasting and ketogenic diets
Defining Prolonged and Intermittent Fasting: International Consensus on Fasting Terminology
NAD <sup>+</sup> supplementation reduces neuroinflammation and cell senescence in a transgenic mouse model of Alzheimer’s disease via cGAS–STING
Intermittent and periodic fasting, longevity and disease
Glucose metabolic crosstalk and regulation in brain function and diseases
TREM2 interacts with TDP-43 and mediates microglial neuroprotection against TDP-43-related neurodegeneration
Neuronal and Astrocytic Extracellular Vesicle Biomarkers in Blood Reflect Brain Pathology in Mouse Models of Alzheimer’s Disease
Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing
Apolipoprotein E and oxidative stress in brain with relevance to Alzheimer's disease
Astrocyte- and Neuron-Derived Extracellular Vesicles from Alzheimer’s Disease Patients Effect Complement-Mediated Neurotoxicity
Topoisomerase 3β knockout mice show transcriptional and behavioural impairments associated with neurogenesis and synaptic plasticity
Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease
Effects of Intermittent Fasting on Health, Aging, and Disease
Senolytic therapy alleviates Aβ-associated oligodendrocyte progenitor cell senescence and cognitive deficits in an Alzheimer’s disease model
NAD+ in Brain Aging and Neurodegenerative Disorders
NAD+ augmentation restores mitophagy and limits accelerated aging in Werner syndrome
NRF2/ARE pathway negatively regulates BACE1 expression and ameliorates cognitive deficits in mouse Alzheimer’s models
SIRT3 mediates hippocampal synaptic adaptations to intermittent fasting and ameliorates deficits in APP mutant mice
Chronic Mild Gut Inflammation Accelerates Brain Neuropathology and Motor Dysfunction in α-Synuclein Mutant Mice
Hallmarks of Brain Aging: Adaptive and Pathological Modification by Metabolic States
Intermittent metabolic switching, neuroplasticity and brain health
NAD <sup>+</sup> supplementation normalizes key Alzheimer’s features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency
Effect of intermittent vs. daily calorie restriction on changes in weight and patient-reported outcomes in people with multiple sclerosis
Notch signaling and neuronal death in stroke
Enhancing and Extending Biological Performance and Resilience
Mitophagy and Alzheimer’s Disease: Cellular and Molecular Mechanisms
Flipping the Metabolic Switch: Understanding and Applying the Health Benefits of Fasting
Brain metabolism in health, aging, and neurodegeneration