Area of research
Molecular Biology · Aging
Research interest
Research interests include CRISPR and Genetic Engineering, Pluripotent Stem Cells Research, Genetics, Aging, and Longevity in Model Organisms, and Epigenetics and DNA Methylation.
Reprogramming the GRHL2-CDK19 axis by gene therapy alleviates prostate aging.
Restoring the FOXO1 geroprotective pathway via seno-resistant mesenchymal progenitor cells alleviates primate epididymal aging.
Genetically engineered senescence-resistant human mesenchymal progenitor cells promote spinal cord injury repair.
Senescence-resistant human mesenchymal progenitor cells counter aging in primates
SIRT5 safeguards against primate skeletal muscle ageing via desuccinylation of TBK1.
Single-cell profiling identifies hair cell SLC35F1 deficiency as a signature of primate cochlear aging
Immunosenescence Inventory-a multi-omics database for immune aging research.
Mitochondrial sirtuins, key regulators of aging.
FOXO3-engineered human mesenchymal stem cells efficiently enhance post-ischemic stroke functional rehabilitation.
A biomarker framework for auditory system aging: the Aging Biomarker Consortium consensus statement
Single-cell profiling identifies hair cell SLC35F1 deficiency as a signature of primate cochlear aging.
A single-cell transcriptomic atlas reveals senescence and inflammation in the post-tuberculosis human lung.
ARID5A orchestrates cardiac aging and inflammation through MAVS mRNA stabilization.
Biomarkers of ageing of humans and non-human primates.
The X-Age Project to construct a Chinese aging clock.
Gene therapy strategies for aging intervention.
Unraveling brain aging through the lens of oral microbiota.
CRISPR-based screening pinpoints H2AZ1 as a driver of senescence in human mesenchymal stem cells.
Research progress in the technology of active substance extraction from red algae
A biomarker framework for auditory system aging: the Aging Biomarker Consortium consensus statement.
Single-nucleus transcriptomics decodes the link between aging and lumbar disc herniation.
Author Correction: SGF29 nuclear condensates reinforce cellular aging.
A framework of biomarkers for adipose tissue aging: a consensus statement by the Aging Biomarker Consortium.
Stress, epigenetics, and aging: Unraveling the intricate crosstalk.
A single-nucleus transcriptomic atlas of primate liver aging uncovers the pro-senescence role of SREBP2 in hepatocytes.
Roles of chromatin and genome instability in cellular senescence and their relevance to ageing and related diseases.
Aging hallmarks of the primate ovary revealed by spatiotemporal transcriptomics.
A biomarker framework for liver aging: the Aging Biomarker Consortium consensus statement
DNA methylation clocks for estimating biological age in Chinese cohorts.
Single-nucleus transcriptomics uncovers a geroprotective role of YAP in primate gingival aging