Area of research
Molecular Biology · Infectious Diseases
Research interest
Research interests include Tuberculosis Research and Epidemiology, Mycobacterium research and diagnosis, Cancer therapeutics and mechanisms, and Biochemical and Molecular Research.
SuFEx-based antitubercular compound irreversibly inhibits Pks13
Identification and Optimization of Novel Inhibitors of the Polyketide Synthase 13 Thioesterase Domain with Antitubercular Activity
CRISPRi chemical genetics and comparative genomics identify genes mediating drug potency in Mycobacterium tuberculosis
Spiropyrimidinetrione DNA Gyrase Inhibitors with Potent and Selective Antituberculosis Activity
Lysyl-tRNA synthetase, a target for urgently needed M. tuberculosis drugs
Genome-wide gene expression tuning reveals diverse vulnerabilities of M. tuberculosis
Dual inhibition of the terminal oxidases eradicates antibiotic‐tolerant Mycobacterium tuberculosis
Plasticity of the Mycobacterium tuberculosis respiratory chain and its impact on tuberculosis drug development
Opposing reactions in coenzyme A metabolism sensitize <i>Mycobacterium tuberculosis</i> to enzyme inhibition
Chemical Genetic Interaction Profiling Reveals Determinants of Intrinsic Antibiotic Resistance in Mycobacterium tuberculosis