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John A. Flygare

Amgen (United States) · US
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Area of research
Oncology · Molecular Biology
Research interest
Research interests include Chemistry, Biochemistry, Apoptosis, Pharmacokinetics, Ubiquitin, and Computational biology.
h-index
—
citations
560
works
7
NIH funding
—
primary concept
—
email
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Recent publications

Cyclodextrin Reduces Intravenous Toxicity of a Model Compound
Journal of Pharmaceutical Sciences 2019cited by 14position: middledoi
Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes
Nature Communications 2018cited by 87position: middledoi
Activity‐based probes for the ubiquitin conjugation–deconjugation machinery: new chemistries, new tools, and new insights
FEBS Journal 2017cited by 120position: middledoi
Activity‐based probes for the multicatalytic proteasome
FEBS Journal 2017cited by 38position: middledoi
Tailoring Small Molecules for an Allosteric Site on Procaspase‐6
ChemMedChem 2013cited by 38position: middledoi
Discovery of a Potent Small-Molecule Antagonist of Inhibitor of Apoptosis (IAP) Proteins and Clinical Candidate for the Treatment of Cancer (GDC-0152)
Journal of Medicinal Chemistry 2012cited by 247position: firstdoi
Dogs Are More Sensitive to Antagonists of Inhibitor of Apoptosis Proteins Than Rats and Humans: A Translational Toxicokinetic/Toxicodynamic Analysis
Toxicological Sciences 2012cited by 16position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Ingrid E. Wertz · Gene Therapy Laboratory3 papers (2017–2018)Matthew Bogyo · Palo Alto University3 papers (2017–2018)David S. Hewings · Gene Therapy Laboratory3 papers (2017–2018)Harvey Wong · McGill University Health Centre2 papers (2012–2019)— · 2 papers (2012–2019)Wayne J. Fairbrother · Amgen (United States)2 papers (2012–2019)Thomas H. Pillow · Amgen (United States)1 papers (2018–2018)Nageshwar Budha · Amgen (United States)1 papers (2012–2012)— · 1 papers (2019–2019)Stephen E. Gould · Gene Therapy Laboratory1 papers (2012–2012)— · 1 papers (2019–2019)— · 1 papers (2018–2018)David Russell · Appalachian State University1 papers (2019–2019)— · 1 papers (2019–2019)— · 1 papers (2018–2018)— · 1 papers (2013–2013)Yinyan Tang · Merck & Co., Inc., Rahway, NJ, USA (United States)1 papers (2013–2013)— · 1 papers (2013–2013)Ron Yu · Yale Cancer Center1 papers (2012–2012)— · 1 papers (2012–2012)
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