Area of research
Molecular Biology · Immunology
Research interest
Research interests include Wnt/β-catenin signaling in development and cancer, Galectins and Cancer Biology, Advanced Electron Microscopy Techniques and Applications, and Axon Guidance and Neuronal Signaling.
Structures of LRP2 reveal a molecular machine for endocytosis
Structure and functional determinants of Rad6–Bre1 subunits in the histone H2B ubiquitin-conjugating complex
Visualization of clustered protocadherin neuronal self-recognition complexes
TOPAZ: A Positive-Unlabeled Convolutional Neural Network CryoEM Particle Picker that can Pick Any Size and Shape Particle
Positive-unlabeled convolutional neural networks for particle picking in cryo-electron micrographs
Homophilic and Heterophilic Interactions of Type II Cadherins Identify Specificity Groups Underlying Cell-Adhesive Behavior
Pathogenic IgG4 autoantibodies from endemic pemphigus foliaceus recognize a desmoglein-1 conformational epitope
Discovery of an O-mannosylation pathway selectively serving cadherins and protocadherins
Mammalian O-mannosylation of cadherins and plexins is independent of protein O-mannosyltransferases 1 and 2
Structural basis of adhesive binding by desmocollins and desmogleins
Structural and energetic determinants of adhesive binding specificity in type I cadherins
Thinking outside the cell: how cadherins drive adhesion
Structures from Anomalous Diffraction of Native Biological Macromolecules
Nectin ectodomain structures reveal a canonical adhesive interface