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Alex J. Noble

University of Otago · NZ
Area of research
Structural Biology · Surfaces, Coatings and Films
Research interest
Research interests include Computer science, Artificial intelligence, Particle (ecology), Nanotechnology, Materials science, and Biophysics.
h-index
citations
1,439
works
12
NIH funding
primary concept
email

Recent publications

Heterogeneous non-canonical nucleosomes predominate in yeast cells in situ
eLife 2023cited by 30position: middledoi
Better, Faster, Cheaper: Recent Advances in Cryo–Electron Microscopy
Annual Review of Biochemistry 2022cited by 160position: middledoi
Waffle Method: A general and flexible approach for improving throughput in FIB-milling
Nature Communications 2022cited by 147position: lastdoi
Architecture of the human erythrocyte ankyrin-1 complex
Nature Structural & Molecular Biology 2022cited by 98position: middledoi
Label-free visual proteomics: Coupling MS- and EM-based approaches in structural biology
Molecular Cell 2022cited by 37position: middledoi
Structural basis for the mechanisms of human presequence protease conformational switch and substrate recognition
Nature Communications 2022cited by 21position: middledoi
Smart data collection for CryoEM
Journal of Structural Biology 2022cited by 17position: middledoi
Topaz-Denoise: general deep denoising models for cryoEM and cryoET
Nature Communications 2020cited by 608position: middledoi
Neural network particle picking and denoising in cryoEM with <i>Topaz</i>
Acta Crystallographica Section A Foundations and Advances 2020cited by 3position: firstdoi
Visualization of clustered protocadherin neuronal self-recognition complexes
Nature 2019cited by 118position: middledoi
Structure of the gene therapy vector, adeno-associated virus with its cell receptor, AAVR
eLife 2019cited by 85position: middledoi
TOPAZ: A Positive-Unlabeled Convolutional Neural Network CryoEM Particle Picker that can Pick Any Size and Shape Particle
Microscopy and Microanalysis 2019cited by 21position: middledoi
Author response: Structure of the gene therapy vector, adeno-associated virus with its cell receptor, AAVR
2019cited by 0position: middledoi
Positive-unlabeled convolutional neural networks for particle picking in cryo-electron micrographs
PubMed 2018cited by 179position: middledoi
The 2.8 Å Electron Microscopy Structure of Adeno-Associated Virus-DJ Bound by a Heparinoid Pentasaccharide
Molecular Therapy — Methods & Clinical Development 2017cited by 35position: middledoi
478. An Essential and Ubiquitous Protein Receptor for AAV; Glycans as Attachment Receptors
Molecular Therapy 2016cited by 0position: middledoi
Automated batch fiducial-less tilt-series alignment in Appion using Protomo
Journal of Structural Biology 2015cited by 76position: firstdoi
The influence of frame alignment with dose compensation on the quality of single particle reconstructions
Journal of Structural Biology 2015cited by 31position: middledoi
COPI gets a fancy new coat
Science 2015cited by 2position: firstdoi
Sar1 Forms Ordered Arrays That Can Facilitate Vesicle Scission in the COPII Pathway
Microscopy and Microanalysis 2015cited by 0position: middledoi
ResLog plots as an empirical metric of the quality of cryo-EM reconstructions
Journal of Structural Biology 2014cited by 93position: middledoi
Insights into the Mechanisms of Membrane Curvature and Vesicle Scission by the Small GTPase Sar1 in the Early Secretory Pathway
Journal of Molecular Biology 2014cited by 54position: middledoi
ResLog Plots: A New Metric for the Quality of Cryo-EM Reconstructions
Microscopy and Microanalysis 2014cited by 0position: middledoi
A pseudoatomic model of the COPII cage obtained from cryo-electron microscopy and mass spectrometry
Nature Structural & Molecular Biology 2012cited by 65position: firstdoi
Structure and Heterogeneity of the COPII Coat
Microscopy and Microanalysis 2012cited by 0position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Scott M. Stagg · Florida State University14 papers (2012–2022)Michael S. Chapman · University of Missouri7 papers (2014–2019)Bridget Carragher · New York Structural Biology Center6 papers (2019–2022)Tristan Bepler · Massachusetts Institute of Technology6 papers (2018–2022)Qing Xie · South China Agricultural University5 papers (2015–2019)Bonnie Berger · Broad Institute5 papers (2018–2020)Clinton S. Potter · Chan Zuckerberg Initiative (United States)5 papers (2019–2022)Omar Davulcu · Pacific Northwest National Laboratory4 papers (2016–2019)Nancy Meyer · Oregon Health & Science University4 papers (2016–2019)Hanaa Hariri · Southwestern Medical Center4 papers (2012–2015)Micah Rapp · Simons Foundation3 papers (2019–2022)Nilakshee Bhattacharya · Florida State University3 papers (2012–2014)Lawrence Shapiro · Columbia College3 papers (2018–2019)Julia Brasch · University of Utah3 papers (2018–2019)Andrew Morin · IIT@MIT2 papers (2018–2019)Larry L. David · Oregon State University2 papers (2019–2019)K. Kelley · Massachusetts Institute of Technology2 papers (2020–2022)Guiqing Hu · Florida State University2 papers (2019–2019) · 2 papers (2019–2019)Oleg Klykov · Utrecht University2 papers (2022–2022)