Area of research
Neurology · Cellular and Molecular Neuroscience
Research interest
Research interests include Biology, Botulism, Neurotoxin, Clostridium botulinum, Thioredoxin, and Neuromuscular junction.
Impact of ageing and disuse on neuromuscular junction and mitochondrial function and morphology: Current evidence and controversies
Defective excitation-contraction coupling and mitochondrial respiration precede mitochondrial Ca2+ accumulation in spinobulbar muscular atrophy skeletal muscle
Toxicology and pharmacology of botulinum and tetanus neurotoxins: an update
Sulfation at Glycopolymer Side Chains Switches Activity at the Macrophage Mannose Receptor (CD206) In Vitro and In Vivo
Models and methods to study Schwann cells
Tetanus and tetanus neurotoxin: From peripheral uptake to central nervous tissue targets
Paper-based electrochemical peptide sensor for on-site detection of botulinum neurotoxin serotype A and C
Botulinum Neurotoxins: Mechanism of Action
Polyglutamine-Expanded Androgen Receptor Alteration of Skeletal Muscle Homeostasis and Myonuclear Aggregation Are Affected by Sex, Age and Muscle Metabolism
Skeletal muscle mTORC1 regulates neuromuscular junction stability
A CXCR4 receptor agonist strongly stimulates axonal regeneration after damage
The role of the single interchains disulfide bond in tetanus and botulinum neurotoxins and the development of antitetanus and antibotulism drugs
Novel Botulinum Neurotoxins: Exploring Underneath the Iceberg Tip
Postnatal Development and Distribution of Sympathetic Innervation in Mouse Skeletal Muscle
Variability in venom composition of European viper subspecies limits the cross-effectiveness of antivenoms
Electrophysiological Recordings of Evoked End-Plate Potential on Murine Neuro-muscular Synapse Preparations
Botulinum Neurotoxins: Biology, Pharmacology, and Toxicology
Historical Perspectives and Guidelines for Botulinum Neurotoxin Subtype Nomenclature
CXCL12α/SDF‐1 from perisynaptic Schwann cells promotes regeneration of injured motor axon terminals
Challenges in searching for therapeutics against Botulinum Neurotoxins
Botulinum neurotoxin C mutants reveal different effects of syntaxin or SNAP-25 proteolysis on neuromuscular transmission
Hsp90 and Thioredoxin-Thioredoxin Reductase enable the catalytic activity of Clostridial neurotoxins inside nerve terminals
Hsp90 is involved in the entry of clostridial neurotoxins into the cytosol of nerve terminals
On the translocation of botulinum and tetanus neurotoxins across the membrane of acidic intracellular compartments
Inhibition of botulinum neurotoxins interchain disulfide bond reduction prevents the peripheral neuroparalysis of botulism
The thioredoxin reductase – Thioredoxin redox system cleaves the interchain disulphide bond of botulinum neurotoxins on the cytosolic surface of synaptic vesicles
Snake and Spider Toxins Induce a Rapid Recovery of Function of Botulinum Neurotoxin Paralysed Neuromuscular Junction
Botulinum neurotoxins: genetic, structural and mechanistic insights
Thioredoxin and Its Reductase Are Present on Synaptic Vesicles, and Their Inhibition Prevents the Paralysis Induced by Botulinum Neurotoxins
Diphtheria toxin conformational switching at acidic pH