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Brian Cleary

Boston University · US
Area of research
Molecular Biology · Biophysics
Research interest
Research interests include Single-cell and spatial transcriptomics, Cell Image Analysis Techniques, Gene expression and cancer classification, and SARS-CoV-2 detection and testing.
h-index
19
citations
3,210
works
46
NIH funding
primary concept
email

Recent publications

Simultaneous CRISPR screening and spatial transcriptomics reveal intracellular, intercellular, and functional transcriptional circuits
Cell 2025cited by 67position: middledoi
Convergence of coronary artery disease genes onto endothelial cell programs
Nature 2024cited by 95position: middledoi
Scalable, compressed phenotypic screening using pooled perturbations
Nature Biotechnology 2024cited by 16position: middledoi
Scalable genetic screening for regulatory circuits using compressed Perturb-seq
Nature Biotechnology 2023cited by 95position: lastdoi
Inferring gene regulation from stochastic transcriptional variation across single cells at steady state
Proceedings of the National Academy of Sciences 2022cited by 57position: middledoi
Mapping the convergence of genes for coronary artery disease onto endothelial cell programs
bioRxiv (Cold Spring Harbor Laboratory) 2022cited by 9position: middledoi
Multimodal pooled Perturb-CITE-seq screens in patient models define mechanisms of cancer immune evasion
Nature Genetics 2021cited by 261position: middledoi
LAMP-Seq enables sensitive, multiplexed COVID-19 diagnostics using molecular barcoding
Nature Biotechnology 2021cited by 79position: middledoi
Using viral load and epidemic dynamics to optimize pooled testing in resource-constrained settings
Science Translational Medicine 2021cited by 58position: firstdoi
Compressed sensing for highly efficient imaging transcriptomics
Nature Biotechnology 2021cited by 49position: firstdoi
Optimal-Transport Analysis of Single-Cell Gene Expression Identifies Developmental Trajectories in Reprogramming
Cell 2019cited by 832position: middledoi
High resolution time series reveals cohesive but short-lived communities in coastal plankton
Nature Communications 2018cited by 186position: middledoi
Efficient Generation of Transcriptomic Profiles by Random Composite Measurements
Cell 2017cited by 118position: firstdoi
Composite measurements and molecular compressed sensing for highly efficient transcriptomics
bioRxiv (Cold Spring Harbor Laboratory) 2017cited by 8position: firstdoi
Systematic mapping of functional enhancer–promoter connections with CRISPR interference
Science 2016cited by 711position: middledoi
Detection of low-abundance bacterial strains in metagenomic datasets by eigengenome partitioning
Nature Biotechnology 2015cited by 166position: firstdoi

Grants

No grants ingested yet.

Frequent collaborators

Aviv Regev · Moscow Institute of Thermal Technology7 papers (2017–2023)Eric S. Lander · Broad Institute7 papers (2016–2022)Jon Bezney · Tulane University4 papers (2021–2025) · 4 papers (2021–2025)Le Cong · Stanford University2 papers (2017–2017)Eric J. Alm · Amgen (United States)2 papers (2015–2018)J Engreitz · Stanford University2 papers (2016–2022) · 2 papers (2022–2022)Loïc Binan · Université de Montréal2 papers (2023–2025)Glen Munson · Broad Institute2 papers (2016–2022)Chris J. Frangieh · Columbia University Irving Medical Center2 papers (2021–2023)Vidya Subramanian · Massachusetts Institute of Technology2 papers (2019–2022)Sharon R. Grossman · Massachusetts Institute of Technology2 papers (2016–2022)James A. Hay · Nuffield Orthopaedic Centre1 papers (2021–2021)Soumya Raychaudhuri · Broad Institute1 papers (2022–2022)Christian K. Soule · Massachusetts Institute of Technology1 papers (2024–2024)Dirk Gevers · Johnson & Johnson (United States)1 papers (2015–2015)Robert T. Manguso · Broad Institute1 papers (2025–2025)Konrad Hochedlinger · Harvard University1 papers (2019–2019)Alex K. Shalek · Broad Institute1 papers (2024–2024)