Area of research
Molecular Biology · Oncology
Research interest
Research focused on Melanoma and PI3K/AKT/mTOR pathway, with related work in Protein kinase B, Antimicrobial peptides, Immune system. Notable publications include 'Lugdunin amplifies innate immune responses in the skin in synergy with host- and microbiota-derived factors', 'miR-137 Inhibits the Invasion of Melanoma Cells through Downregulation of Multiple Oncogenic Target Genes', and 'PI3K Pathway Inhibition Achieves Potent Antitumor Activity in Melanoma Brain Metastases In Vitro and In Vivo'.
NOD2-Induced IκBζ Mediates a Protective Host Response against Epicutaneous Staphylococcus aureus Infection
naRNA-LL37 composite DAMPs define sterile NETs as self-propagating drivers of inflammation
Skin Cancer Induction by the Antimycotic Drug Voriconazole Is Caused by Impaired DNA Damage Detection Due to Chromatin Compaction
IL-17 Signaling in Keratinocytes Orchestrates the Defense against Staphylococcus aureus Skin Infection
Targeting the Y-box Binding Protein-1 Axis to Overcome Radiochemotherapy Resistance in Solid Tumors
Blocking Y-Box Binding Protein-1 through Simultaneous Targeting of PI3K and MAPK in Triple Negative Breast Cancers
Lugdunin amplifies innate immune responses in the skin in synergy with host- and microbiota-derived factors
PI3K Pathway Inhibition Achieves Potent Antitumor Activity in Melanoma Brain Metastases <i>In Vitro</i> and <i>In Vivo</i>
522 Induction of the progeroid/cancer prone XP-like phenotype by an antimycotic drug is mediated via reversible downregulation of DNA repair, an update
Processing of Laminin α Chains Generates Peptides Involved in Wound Healing and Host Defense
Quantitative Proteomics of the Human Skin Secretome Reveal a Reduction in Immune Defense Mediators in Ectodermal Dysplasia Patients
YBX1 Is a Modulator of MIA/CD-RAP-Dependent Chondrogenesis
Melanoma inhibitory activity promotes melanoma development through activation of <scp>YBX</scp>1
miR-137 Inhibits the Invasion of Melanoma Cells through Downregulation of Multiple Oncogenic Target Genes
MAPK and PI3K/AKT mediated YB‐1 activation promotes melanoma cell proliferation which is counteracted by an autoregulatory loop