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Daniel R. Goulet

Massachusetts Institute of Technology · US
Area of research
Computational Theory and Mathematics · Molecular Biology
Research interest
Research focused on CRISPR and Pancreatic cancer, with related work in Cancer research, In vivo, Immune system. Notable publications include 'Microenvironmental IL-6 inhibits anti-cancer immune responses generated by cytotoxic chemotherapy', 'Leukemia-intrinsic determinants of CAR-T response revealed by iterative in vivo genome-wide CRISPR screening', and 'FOXA1 and adaptive response determinants to HER2 targeted therapy in TBCRC 036'.
h-index
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citations
196
works
5
NIH funding
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primary concept
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email
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Recent publications

Abstract B060: Unveiling resistance mechanisms to CAR T-cell therapy in pancreatic cancer through in vivo CRISPR/Cas9 knockout screening
Cancer Research 2024cited by 0position: middledoi
Abstract B039: Elucidating the tumor-driven mechanisms of resistance to immunotherapies in pancreatic cancer through in vivo CRISPR/Cas9 knockout screening
Cancer Immunology Research 2024cited by 0position: middledoi
Leukemia-intrinsic determinants of CAR-T response revealed by iterative in vivo genome-wide CRISPR screening
Nature Communications 2023cited by 24position: middledoi
Microenvironmental IL-6 inhibits anti-cancer immune responses generated by cytotoxic chemotherapy
Nature Communications 2021cited by 148position: middledoi
FOXA1 and adaptive response determinants to HER2 targeted therapy in TBCRC 036
npj Breast Cancer 2021cited by 24position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Michael T. Hemann · Massachusetts Institute of Technology4 papers (2021–2024)P Leclerc · Massachusetts Institute of Technology3 papers (2023–2024)Riley D. Hellinger · Massachusetts Institute of Technology3 papers (2023–2024)Julia Fröse · Medieval Academy of America3 papers (2021–2024)Charles A. Whittaker · Massachusetts Institute of Technology3 papers (2023–2024)Adam Langenbucher · Allen Institute2 papers (2024–2024)Yunpeng Liu-Lupo · Massachusetts Institute of Technology1 papers (2023–2023)Audrey J. Muscato · Massachusetts Institute of Technology1 papers (2023–2023)Robert T. Manguso · Broad Institute1 papers (2023–2023)Azucena Ramos · Massachusetts Institute of Technology1 papers (2023–2023)Julia Froese · IIT@MIT1 papers (2024–2024)Michael E. Birnbaum · Ragon Institute of MGH, MIT and Harvard1 papers (2023–2023)Aviv Regev · Moscow Institute of Thermal Technology1 papers (2023–2023)Matthew G. Vander Heiden · Broad Institute1 papers (2023–2023)Eric H. Bent · Massachusetts Institute of Technology1 papers (2021–2021)Khloe S. Gordon · Massachusetts Institute of Technology1 papers (2023–2023)Keith P. Eidell · Massachusetts Institute of Technology1 papers (2023–2023)Keene L. Abbott · Massachusetts Institute of Technology1 papers (2023–2023)Marcela V. Maus · Harvard University1 papers (2023–2023)Iris Zhuang · Massachusetts Institute of Technology1 papers (2021–2021)