Area of research
Cell Biology · Molecular Biology
Research interest
Research focused on Ubiquitin and Carcinogenesis, with related work in Ubiquitin ligase, Glutamine, Cell biology. Notable publications include 'The tRNA methyltransferase Dnmt2 is required for accurate polypeptide synthesis during haematopoiesis', 'YAP and β-Catenin Cooperate to Drive Oncogenesis in Basal Breast Cancer', and 'Sequential Poly-ubiquitylation by Specialized Conjugating Enzymes Expands the Versatility of a Quality Control Ubiquitin Ligase'.
Systematic evaluation of neoepitope predictions challenges clinically observed T-cell responses and their impact on immune evasion
Autophagy selectively clears ER in TNF-α-induced muscle atrophy
Multicenter Longitudinal Quality Assessment of MS-Based Proteomics in Plasma and Serum
Multicenter evaluation of label-free quantification in human plasma on a high dynamic range benchmark set
Intestinal interstitial fluid isolation provides novel insight into the human host-microbiome interface
The proteogenomic landscape of multiple myeloma reveals insights into disease biology and therapeutic opportunities
K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors
Sex-specific microglia state in the Neuroligin-4 knock-out mouse model of autism spectrum disorder
Small molecule inhibiting microglial nitric oxide release could become a potential treatment for neuroinflammation
Response to: Correspondence on 'H3.3K27M mutation is not a suitable target for immunotherapy in HLA-A2+ patients with diffuse midline glioma' by Chheda <i>et al</i>
Identification of tumor-specific MHC ligands through improved biochemical isolation and incorporation of machine learning
Proteomic profiling reveals CDK6 upregulation as a targetable resistance mechanism for lenalidomide in multiple myeloma
H3.3K27M mutation is not a suitable target for immunotherapy in HLA-A2<sup>+</sup> patients with diffuse midline glioma
Immune Phenotypes and Target Antigens of Clonally Expanded Bone Marrow T Cells in Treatment-Naïve Multiple Myeloma
A member of the tryptophan-rich protein family is required for efficient sequestration of Plasmodium berghei schizonts
YAP and β-Catenin Cooperate to Drive Oncogenesis in Basal Breast Cancer
A Universal Peptide Matrix Interactomics Approach to Disclose Motif-Dependent Protein Binding
The newly identified MEK1 tyrosine phosphorylation target MACC1 is druggable by approved MEK1 inhibitors to restrict colorectal cancer metastasis
Peritoneal metastasis of colorectal cancer (pmCRC): identification of predictive molecular signatures by a novel preclinical platform of matching pmCRC PDX/PD3D models
Sequential Poly-ubiquitylation by Specialized Conjugating Enzymes Expands the Versatility of a Quality Control Ubiquitin Ligase
Loss of DJ-1 impairs antioxidant response by altered glutamine and serine metabolism
The <scp>tRNA</scp> methyltransferase Dnmt2 is required for accurate polypeptide synthesis during haematopoiesis