Area of research
Physiology · Neurology
Research interest
Research interests include Alzheimer's disease research and treatments, Dementia and Cognitive Impairment Research, Amyotrophic Lateral Sclerosis Research, and Parkinson's Disease Mechanisms and Treatments.
Safety and efficacy of long-term gantenerumab treatment in dominantly inherited Alzheimer's disease: an open-label extension of the phase 2/3 multicentre, randomised, double-blind, placebo-controlled platform DIAN-TU trial
Comprehensive cross-sectional and longitudinal comparisons of plasma glial fibrillary acidic protein and neurofilament light across FTD spectrum disorders
Sex differences in clinical phenotypes of behavioral variant frontotemporal dementia
Large-scale network analysis of the cerebrospinal fluid proteome identifies molecular signatures of frontotemporal lobar degeneration
Reduction of sphingomyelinase activity associated with progranulin deficiency and frontotemporal dementia
The relationship of soluble tau species with Alzheimer's disease amyloid plaque removal and tau pathology
Downstream Biomarker Effects of Gantenerumab or Solanezumab in Dominantly Inherited Alzheimer Disease
Baseline levels and longitudinal changes in plasma Aβ42/40 among Black and white individuals
Machine learning reveals prominent spontaneous behavioral changes and treatment efficacy in humanized and transgenic Alzheimer's disease models
Reliability and Validity of Smartphone Cognitive Testing for Frontotemporal Lobar Degeneration
Multimerization of TREM2 is impaired by Alzheimer's disease–associated variants
Quantifying Putative Retinal Gliosis in Preclinical Alzheimer's Disease
X‐chromosome-wide association study for Alzheimer’s disease
Latozinemab, a novel progranulin-elevating therapy for frontotemporal dementia
Evaluation of the Electronic Clinical Dementia Rating for Dementia Screening
Preclinical Interventions in Mouse Models of Frontotemporal Dementia Due to Progranulin Mutations
Longitudinal head-to-head comparison of 11C-PiB and 18F-florbetapir PET in a Phase 2/3 clinical trial of anti-amyloid-β monoclonal antibodies in dominantly inherited Alzheimer’s disease
Relationships of Cognitive Measures with Cerebrospinal Fluid but Not Imaging Biomarkers of Alzheimer Disease Vary between Black and White Individuals
Temporal order of clinical and biomarker changes in familial frontotemporal dementia
Comprehensive cross-sectional and longitudinal analyses of plasma neurofilament light across FTD spectrum disorders
TAU ablation in excitatory neurons and postnatal TAU knockdown reduce epilepsy, SUDEP, and autism behaviors in a Dravet syndrome model
ASLPrep: a platform for processing of arterial spin labeled MRI and quantification of regional brain perfusion
Periodontal Infection Aggravates C1q-Mediated Microglial Activation and Synapse Pruning in Alzheimer’s Mice
Dissection of the polygenic architecture of neuronal Aβ production using a large sample of individual iPSC lines derived from Alzheimer’s disease patients
A trial of gantenerumab or solanezumab in dominantly inherited Alzheimer’s disease
Plasma Neurofilament Light for Prediction of Disease Progression in Familial Frontotemporal Lobar Degeneration
Proposed research criteria for prodromal behavioural variant frontotemporal dementia
Aberrant regulation of a poison exon caused by a non-coding variant in a mouse model of Scn1a-associated epileptic encephalopathy
Dysregulated clock gene expression and abnormal diurnal regulation of hippocampal inhibitory transmission and spatial memory in amyloid precursor protein transgenic mice
Correlation between Alzheimer’s disease and type 2 diabetes using non-negative matrix factorization
UAB Alzheimer's Disease Research Center
Circadian changes in network excitability and Alzheimer disease pathogenesis
Circadian changes in network excitability and Alzheimer disease pathogenesis
Circadian changes in network excitability and Alzheimer disease pathogenesis
Circadian changes in network excitability and Alzheimer disease pathogenesis
Circadian changes in network excitability and Alzheimer disease pathogenesis
Circadian changes in network excitability and Alzheimer disease pathogenesis
Circadian changes in network excitability and Alzheimer disease pathogenesis
Circadian changes in network excitability and Alzheimer disease pathogenesis
Circadian changes in network excitability and Alzheimer disease pathogenesis
UAB Alzheimer's Disease Research Center
UAB Alzheimer's Disease Research Center
Circadian changes in network excitability and Alzheimer disease pathogenesis
BIN1, Interneuron Activity, and Network Dysfunction in Alzheimer Disease
UAB Training Program in Neurodegeneration
UAB Training Program in Neurodegeneration
UAB Training Program in Neurodegeneration
UAB Training Program in Neurodegeneration