Area of research
Pharmacology · Computational Theory and Mathematics
Research interest
Research focused on Drug discovery and Natural product, with related work in Drug, Blueprint, Oxidative stress. Notable publications include 'Towards the sustainable discovery and development of new antibiotics', 'Artificial intelligence for natural product drug discovery', and 'Citraconate inhibits ACOD1 (IRG1) catalysis, reduces interferon responses and oxidative stress, and modulates inflammation and cell metabolism'.
Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor
Novel 6-hydroxybenzothiazol-2-carboxamides as potent and selective monoamine oxidase B inhibitors endowed with neuroprotective activity
Artificial intelligence for natural product drug discovery
NRF2 activators inhibit influenza A virus replication by interfering with nucleo-cytoplasmic export of viral RNPs in an NRF2-independent manner
Clean Synthetic Strategies to Biologically Active Molecules from Lignin: A Green Path to Drug Discovery**
Identification of inhibitors targeting the energy-coupling factor (ECF) transporters
Citraconate inhibits ACOD1 (IRG1) catalysis, reduces interferon responses and oxidative stress, and modulates inflammation and cell metabolism
Discovery of the First Selective Nanomolar Inhibitors of ERAP2 by Kinetic Target‐Guided Synthesis
Towards the sustainable discovery and development of new antibiotics
Tracheal brush cells release acetylcholine in response to bitter tastants for paracrine and autocrine signaling
Glucansucrase (mutant) enzymes from Lactobacillus reuteri 180 efficiently transglucosylate Stevia component rebaudioside A, resulting in a superior taste
Fine-tuning Nanocarriers Specifically toward Cargo: A Competitive Study on Solubilizing Related Photosensitizers for Photodynamic Therapy
Infrared Absorption Spectrum of Brushite from First Principles
A Natural‐Product Switch for a Dynamic Protein Interface
Combinatorial Screening for Specific Drug Solubilizers with Switchable Release Profiles
Exploiting Specific Interactions toward Next-Generation Polymeric Drug Transporters