Area of research
Molecular Biology · Surgery
Research interest
Research interests include RNA modifications and cancer, PI3K/AKT/mTOR signaling in cancer, Cholesterol and Lipid Metabolism, and RNA Research and Splicing.
Direct sensing of dietary ω-6 linoleic acid through FABP5-mTORC1 signaling
Nutrient control of growth and metabolism through mTORC1 regulation of mRNA splicing
FAM120A couples SREBP-dependent transcription and splicing of lipogenesis enzymes downstream of mTORC1
Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression
Suppression of nuclear GSK3 signaling promotes serine/one-carbon metabolism and confers metabolic vulnerability in lung cancer cells
Decreased Enterobacteriaceae translocation due to gut microbiota remodeling mediates the alleviation of premature aging by a high‐fat diet
mTORC1 promotes cell growth via m6A-dependent mRNA degradation
mTORC1-chaperonin CCT signaling regulates m <sup>6</sup> A RNA methylation to suppress autophagy
mTORC1 Promotes Metabolic Reprogramming by the Suppression of GSK3-Dependent Foxk1 Phosphorylation
Post-transcriptional Regulation of De Novo Lipogenesis by mTORC1-S6K1-SRPK2 Signaling
Membrane-enabled dimerization of the intrinsically disordered cytoplasmic domain of ADAM10
Specific Inhibition Of Ectodomain Shedding Of GPIba By Targeting Its Shedding Cleavage Site