Area of research
Cancer Research · Geriatrics and Gerontology
Research interest
Research interests include Sirtuins and Resveratrol in Medicine, Cancer, Hypoxia, and Metabolism, CRISPR and Genetic Engineering, and Cancer, Lipids, and Metabolism.
Direct sensing of dietary ω-6 linoleic acid through FABP5-mTORC1 signaling
The emerging role of dysregulated propionate metabolism and methylmalonic acid in metabolic disease, aging, and cancer
FAM120A couples SREBP-dependent transcription and splicing of lipogenesis enzymes downstream of mTORC1
Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression
Suppression of nuclear GSK3 signaling promotes serine/one-carbon metabolism and confers metabolic vulnerability in lung cancer cells
Metabolite activation of tumorigenic signaling pathways in the tumor microenvironment
Decreased Enterobacteriaceae translocation due to gut microbiota remodeling mediates the alleviation of premature aging by a high‐fat diet
Pooled CRISPR Screens in <i>Drosophila</i> Cells
A Membrane Transporter Is Required for Steroid Hormone Uptake in Drosophila
Pooled genome-wide CRISPR screening for basal and context-specific fitness gene essentiality in Drosophila cells
Improved detection of synthetic lethal interactions in <i>Drosophila</i> cells using variable dose analysis (VDA)