Area of research
Molecular Biology · Cancer Research
Research interest
Research focused on Cell biology and Stromal cell, with related work in Immune system, RANKL, Microglia. Notable publications include 'Mining TCGA database for genes of prognostic value in glioblastoma microenvironment', 'LGR4 is a receptor for RANKL and negatively regulates osteoclast differentiation and bone resorption', and 'Dual Antiplatelet Treatment up to 72 Hours after Ischemic Stroke'.
The lactate receptor HCAR1 drives the recruitment of immunosuppressive PMN-MDSCs in colorectal cancer
Preclinical evaluation of AGT mRNA replacement therapy for primary hyperoxaluria type I disease
Author Correction: The lactate receptor HCAR1 drives the recruitment of immunosuppressive PMN-MDSCs in colorectal cancer
Engineering IscB to develop highly efficient miniature editing tools in mammalian cells and embryos
Immediate- or Delayed-Intensive Statin in Acute Cerebral Ischemia
Author Correction: Adenine transversion editors enable precise, efficient A•T-to-C•G base editing in mammalian cells and embryos
Dual Antiplatelet Treatment up to 72 Hours after Ischemic Stroke
Adenine transversion editors enable precise, efficient A•T-to-C•G base editing in mammalian cells and embryos
Rna M<sup>6</sup>a Methylation Regulates Glycolysis of Beige Fat and Contributes to Systemic Metabolic Homeostasis
Microglial debris is cleared by astrocytes via C4b-facilitated phagocytosis and degraded via RUBICON-dependent noncanonical autophagy in mice
Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidates for targeted treatment
Generation of offspring-producing 3D ovarian organoids derived from female germline stem cells and their application in toxicological detection
Epigenetic inactivation of ERF reactivates γ-globin expression in β-thalassemia
Base Editing Mediated Generation of Point Mutations Into Human Pluripotent Stem Cells for Modeling Disease
Mining TCGA database for genes of prognostic value in glioblastoma microenvironment
Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility
Recurrent ECSIT mutation encoding V140A triggers hyperinflammation and promotes hemophagocytic syndrome in extranodal NK/T cell lymphoma
Dysfunction of Myosin Light‐Chain 4 (MYL4) Leads to Heritable Atrial Cardiomyopathy With Electrical, Contractile, and Structural Components: Evidence From Genetically‐Engineered Rats
The 5-Hydroxymethylcytosine (5hmC) Reader UHRF2 Is Required for Normal Levels of 5hmC in Mouse Adult Brain and Spatial Learning and Memory
LGR4 is a receptor for RANKL and negatively regulates osteoclast differentiation and bone resorption
Heritable expansion of the genetic code in mouse and zebrafish
Loss of KLF14 triggers centrosome amplification and tumorigenesis
Role of MUC20 overexpression as a predictor of recurrence and poor outcome in colorectal cancer
Abnormal expression of GADD45B in human colorectal carcinoma