Area of research
Molecular Biology · Cellular and Molecular Neuroscience
Research interest
Research focused on Conotoxin and Venom, with related work in Conus, Dorsal root ganglion, Induced pluripotent stem cell. Notable publications include 'Marine Toxins Targeting Kv1 Channels: Pharmacological Tools and Therapeutic Scaffolds', 'Analgesic conopeptides targeting G protein-coupled receptors reduce excitability of sensory neurons', and 'Molecular and Functional Characterization of Neurogenin-2 Induced Human Sensory Neurons'.
Cellular heterogeneity of pluripotent stem cell-derived cardiomyocyte grafts is mechanistically linked to treatable arrhythmias
A previously unrecognized superfamily of macro-conotoxins includes an inhibitor of the sensory neuron calcium channel Cav2.3
Automated Patch Clamp Screening of Amiloride and 5- <i>N</i> , <i>N</i> -Hexamethyleneamiloride Analogs Identifies 6-Iodoamiloride as a Potent Acid-Sensing Ion Channel Inhibitor
Evidence of Cytolysin A nanopore incorporation in mammalian cells assessed by a graphical user interface
Multitarget nociceptor sensitization by a promiscuous peptide from the venom of the King Baboon spider
Investigation of CACNA1I Cav3.3 Dysfunction in Hemiplegic Migraine
Analgesic α-Conotoxin Binding Site on the Human GABAB Receptor
µ-Theraphotoxin Pn3a inhibition of CaV3.3 channels reveals a novel isoform-selective drug binding site
Small-molecule mimicry hunting strategy in the imperial cone snail, <i>Conus imperialis</i>
Pathophysiological metabolic changes associated with disease modify the proarrhythmic risk profile of drugs with potential to prolong repolarisation
Analgesic α‐conotoxins modulate native and recombinant GIRK1/2 channels via activation of GABA <sub>B</sub> receptors and reduce neuroexcitability
In Vivo Survival and Differentiation of Friedreich Ataxia iPSC-Derived Sensory Neurons Transplanted in the Adult Dorsal Root Ganglia
Spider Venom Peptide Pn3a Inhibition of Primary Afferent High Voltage-Activated Calcium Channels
Marine Toxins Targeting Kv1 Channels: Pharmacological Tools and Therapeutic Scaffolds
Molecular and Functional Characterization of Neurogenin-2 Induced Human Sensory Neurons
Ketamine inhibits synaptic transmission and nicotinic acetylcholine receptor-mediated responses in rat intracardiac ganglia in situ
Analgesic transient receptor potential vanilloid‐1‐active compounds inhibit native and recombinant T‐type calcium channels
Structural basis of the potency and selectivity of Urotoxin, a potent Kv1 blocker from scorpion venom
Extremely Potent Block of Bacterial Voltage-Gated Sodium Channels by µ-Conotoxin PIIIA
Novel analgesic ω-conotoxins from the vermivorous cone snail Conus moncuri provide new insights into the evolution of conopeptides
Batrachotoxin acts as a stent to hold open homotetrameric prokaryotic voltage-gated sodium channels
NMR Structure of μ-Conotoxin GIIIC: Leucine 18 Induces Local Repacking of the N-Terminus Resulting in Reduced NaV Channel Potency
Analgesic conopeptides targeting G protein-coupled receptors reduce excitability of sensory neurons
Inhibition of human N‐ and T‐type calcium channels by an<i>ortho</i>‐phenoxyanilide derivative, MONIRO‐1