Area of research
Endocrinology, Diabetes and Metabolism · Surgery
Research interest
Research interests include Pancreatic function and diabetes, Hyperglycemia and glycemic control in critically ill and hospitalized patients, Diabetes and associated disorders, and Diabetes Management and Research.
Epigenetic adaptation of beta cells across lifespan and disease
Acinar Metaplastic Cells Generate Semi-Homogeneous Niches and Interact With Immune Cells
Atlas of imprinted and allele-specific DNA methylation in the human body
Exploring penetrance of clinically relevant variants in over 800,000 humans from the Genome Aggregation Database
G6PC2 controls glucagon secretion by defining the set point for glucose in pancreatic α cells
Epigenetic liquid biopsies reveal endothelial turnover and erythropoiesis in asymptomatic COVID-19
RNA editing deficiency models differential immunogenicity of pancreatic α- and β-cells
Latent plasticity of the human pancreas across development, health, and disease
Genetic/epigenetic DNA markers for linking suspects and tissues in complex crime scenes
Author Correction: A genomic mutational constraint map using variation in 76,156 human genomes
CelFiE-ISH: a probabilistic model for multi-cell type deconvolution from single-molecule DNA methylation haplotypes
DNA Methylation–Based Assessment of Cell Composition in Human Pancreas and Islets
The IsletTester Mouse: An Immunodeficient Model With Stable Hyperglycemia for the Study of Human Islets
Characterization of metabolic alterations in the lean metabolically unhealthy alpha defensin transgenic mice
Author Correction: CelFiE-ISH: a probabilistic model for multi-cell type deconvolution from single-molecule DNA methylation haplotypes
A genomic mutational constraint map using variation in 76,156 human genomes
A DNA methylation atlas of normal human cell types
Elevated cfDNA after exercise is derived primarily from mature polymorphonuclear neutrophils, with a minor contribution of cardiomyocytes
Disrupted RNA editing in beta cells mimics early-stage type 1 diabetes
Accurate age prediction from blood using a small set of DNA methylation sites and a cohort-based machine learning algorithm
Megakaryocyte- and erythroblast-specific cell-free DNA patterns in plasma and platelets reflect thrombopoiesis and erythropoiesis levels
Protein biomarkers and alternatively methylated cell-free DNA detect early stage pancreatic cancer
Inferring compound heterozygosity from large-scale exome sequencing data
The DNA methylome of human vascular endothelium and its use in liquid biopsies
Hyperglucagonaemia in diabetes: altered amino acid metabolism triggers mTORC1 activation, which drives glucagon production
Short report: Plasma based biomarkers detect radiation induced brain injury in cancer patients treated for brain metastasis: A pilot study
Beta‐cell death and dysfunction drives hyperglycaemia in organ donors
Extensive elimination of acinar cells during normal postnatal pancreas growth
Large-scale sequencing identifies multiple genes and rare variants associated with Crohn’s disease susceptibility
Liquid biopsy reveals collateral tissue damage in cancer